Effect of acupuncture on nausea and/or vomiting during and after cesarean section in comparison with ondansetron
Effect of acupuncture on nausea and/or vomiting during and after cesarean section in comparison with ondansetron
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DOI：
10.1007/s00540-011-1198-0
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发表时间：
2011-10-01
影响因子：
2.8
通讯作者：
Ahmady, Mona S.
中科院分区：
文献类型：
--
作者：
El-Deeb, Alaa M.;Ahmady, Mona S.
目的：针灸治疗术后恶心呕吐（PONV）。方法将450例择期剖宫产产妇随机分为两组，每组100例，分别采用电针P6穴位和恩丹西酮穴位，观察两组产妇术中、术后呕吐的发生率及对术后呕吐的影响（心包6）脊髓麻醉前30分钟（组III; n = 150），或脊髓麻醉前30分钟（组II; n = 150），或安慰剂（组II; n = 150），昂丹司琼4 mg。恶心和呕吐进行了评估，并记录术中和术后24 h由一个独立的anesthesist.Results三组没有显着不同的术中麻黄碱剂量和手术时间。在手术期间和术后6小时，活性治疗组（II、III）的恶心和呕吐发生率在统计学上显著降低。两组术后6 ~ 24 h恶心呕吐发生率无统计学显著差异。积极治疗组患者对PONV控制的满意度高于I组。结论电刺激在预防腰麻下剖宫产术中及术后PONV方面与昂丹司琼相当，并能提高患者满意度。
Purpose Acupuncture has been used for the management of postoperative nausea and vomiting (PONV). This study compared the effect of electrical acustimulation with ondansetron for preventing intraoperative and postoperative emetic symptoms and improving patient satisfaction.Methods After gaining ethical approval, 450 parturients scheduled for elective cesarean delivery were randomly allocated to receive either electrical stimulation using P6 acupoint (pericardium 6) bilaterally for 30 min before spinal anesthesia (group III; n = 150), or 4 mg ondansetron 30 min before spinal anesthesia (group II; n = 150), or placebo (group II; n = 150). Nausea and vomiting were evaluated and recorded intraoperatively and postoperative for 24 h by an independent anesthetist.Results The three groups were not significantly different with respect to intraoperative ephedrine dose and duration of surgery. Nausea and vomiting occurred statistically significantly less often in the active treatment groups (II, III) during operation and for 6 h postoperatively. There was no statistically significant difference between the groups in the incidence of nausea and vomiting from 6 to 24 h postoperatively. Patient satisfaction with PONV control was higher with the active treatment groups compared with group I.Conclusion Electrical acustimulation is comparable to ondansetron in prevention of PONV during and after cesarean delivery under spinal anesthesia and in improving patient satisfaction.