Prognostic significance of atrial fibrillation/atrial flutter in patients with acute myocardial infarction treated with percutaneous coronary intervention
Prognostic significance of atrial fibrillation/atrial flutter in patients with acute myocardial infarction treated with percutaneous coronary intervention
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DOI：
10.1016/j.amjcard.2003.07.021
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发表时间：
2003-11-15
影响因子：
2.8
通讯作者：
Hori, M
中科院分区：
文献类型：
--
作者：
Kinjo, K;Sato, H;Hori, M
心房颤动（AF）是急性心肌梗死（AMI）后常见的并发症，与溶栓前和溶栓后住院和长期死亡率增加相关。目前的治疗，包括经皮冠状动脉介入治疗（PCI），是有效地降低死亡率的AMI患者。然而，很少有人知道房颤的发病率和预后意义的AMI患者接受PCI治疗。我们评估了2,475例连续AMI患者，这些患者在发病后24小时内接受了PCI，并入选了大坂急性冠状动脉功能不全研究。根据是否存在AF或房扑，将患者分为2组。房颤发生率为12.0%。AF患者年龄较大，Killip分级较高，既往心肌梗死和脑血管病的发生率较高，收缩压< 100 mm Hg and heart rates of >≥ 100次/min，多支血管病变，梗死相关动脉的再灌注较差。AF患者的住院时间（16.0% vs 6.7%，p
Atrial fibrillation (AF) is a frequent complication after acute myocardial infarction (AMI) that has been associated with increased in-hospital and long-term mortality rates in the prethrombolytic and thrombolytic eras. Current therapies, including percutaneous coronary intervention (PCI), are effective in reducing mortality in patients with AMI. However, little is known concerning the incidence and prognostic significance of AF in patients with AMI who are treated with PCI. We evaluated 2,475 consecutive patients with AMI who underwent PCI within 24 hours after onset and who were enrolled in the Osaka Acute Coronary Insufficiency Study. Patients were categorized into 2 groups according to the presence of AF or atrial flutter. The incidence of AF was 12.0%. Patients with AF were older, were in higher Killip classes, had higher rates of previous myocardial infarction and previous cerebrovascular disease, had systolic blood pressure of < 100 mm Hg and heart rates of >= 100 beats/min, multivessel disease, and had poorer reperfusion of the infarct-related artery than those without AF. Patients with AF had higher in-hospital (16.0% vs 6.7%, p