Identity crisis? The need for systematic gene IDs.
Identity crisis? The need for systematic gene IDs.
复制标题
身份危机?
DOI:
10.1016/j.pt.2011.02.007
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发表时间:
2011
影响因子:
9.6
通讯作者:
Stuart,KennethD
中科院分区:
文献类型:
--
作者:
Parsons,Marilyn;Myler,PeterJ;Berriman,Matthew;Roos,DavidS;Stuart,KennethD
Recent years have seen an explosion in the availability of protozoan pathogen genome sequences. Although data regarding the underlying genome sequence remain relatively stable after the initial draft, understanding of specific gene function is increasing rapidly. This dichotomy is reflected in the relative stability of systematic gene identifiers (SysIDs**SysIDs: SysIDs are found in differently named fields in each database: EuPathDB (GeneID), GeneDB (Systematic Name or Gene), TDRTargets (Name or Identifier/Accession) and UniPro (Accession Number). They are provided in GenBank Entrez Gene in the ‘ocus tag' or ‘gene symbol' field.) in genome sequence databases, as compared to evolving and/or conflicting gene and gene product names. GenBank/EMBL/DDBJ accession numbers are important, but most protozoan parasite researchers use organism-based databases such as EuPathDB or GeneDB as their immediate resource for gene-based information because they not only provide sequence information but also functional information and links to references. Reference to SysIDs therefore provides a valuable bridge to this repository of information.