Influence of fluorapatite minor additions on behavior of hydroxyapatite ceramics
Influence of fluorapatite minor additions on behavior of hydroxyapatite ceramics
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氟磷灰石微量添加对羟基磷灰石陶瓷性能的影响
DOI：
10.1023/b:jmsm.0000015490.32304.f4
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Å. Rosengren
中科院分区：
文献类型：
--
作者：
S. Barinov;F. Rustichelli;V. Orlovskii;A. Lodini;S. Oscarsson;S. Firstov;S. Tumanov;P. Millet;Å. Rosengren
众所周知，与纯羟基磷灰石陶瓷相比，氟化羟基磷灰石不易被体液溶解，从而增强了在体内条件下抗生物降解的能力。本文研究了微量添加超细氟磷灰石（10%）对羟基磷灰石陶瓷烧结性能和力学性能的影响。用不同氟磷灰石含量的样品进行成骨样细胞活力和增殖的体外测试。发现氟磷灰石的加入阻碍了烧结收缩，降低了强度，但一般不会对细胞的活力产生负面影响。
Fluorinated hydroxyapatite is known to be less soluble by body fluids, resulting in enhanced resistance to biodegradation in vivo conditions, as compared to the pure hydroxyapatite ceramics. The present work was aimed at the investigation of the effect of minor additions of ultrafine fluorapatite (up to 10 wt %) on the sintering behavior and mechanical properties of hydroxyapatite ceramics. In vitro testing for the osteoblast-like cells viability and proliferation was performed with the samples of varying fluorapatite content. It was found that the fluorapatite addition hinders the sintering shrinkage and lowers the strength, but does not generally affect negatively the viability of the cells.