Activation and inactivation steps in the visual transduction pathway
Activation and inactivation steps in the visual transduction pathway
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DOI：
10.1016/s0959-4388(97)80029-3
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发表时间：
1997-08
影响因子：
5.7
通讯作者：
K. Palczewski;J. C. Saari
中科院分区：
文献类型：
--
作者：
K. Palczewski;J. C. Saari
最近的遗传、生化和电生理学证据为视觉中负责漂白脱敏的物质的分子特性提供了见解。对导致延迟暗适应的分子缺陷的研究表明，这种脱敏物质被视紫红质激酶和/或arrestin识别，因此很可能是一种由全反式视网膜和视蛋白组成的复合体。
Recent genetic, biochemical and electrophysiological evidence has provided insights into the molecular identity of the substance responsible for bleaching desensitization in vision. Studies examining the molecular defects that cause delayed dark adaptation suggest that the desensitizing substance is recognized by rhodopsin kinase and/or arrestin and, therefore, is probably a complex comprising all-trans-retinal and opsin.