Dynamic contrast-enhanced fluorescence imaging compared with MR imaging in evaluating bone perfusion during open orthopedic surgery.
Dynamic contrast-enhanced fluorescence imaging compared with MR imaging in evaluating bone perfusion during open orthopedic surgery.
复制标题
动态对比增强荧光成像与磁共振成像在评估开放骨科手术期间骨灌注方面的比较。
DOI：
10.1117/12.2608382
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Jiang,Shudong
中科院分区：
文献类型：
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作者：
Tang,Yue;Sin,JessicaM;Gitajn,ILeah;Cao,Xu;Han,Xinyue;Elliott,JonathanT;Yu,Xiaohan;Christian,MelanieL;Bateman,Logan;Chockbengboun,Theresa;Henderson,EricR;Pogue,BrianW;Jiang,Shudong
在3例下肢骨感染病例中，几乎同时进行了基于ICG的动态对比增强荧光成像（DCE-FI）和术中DCE-MRI，以研究这两种成像模式之间的关系，用于评估开放性骨科手术期间的骨血流灌注。两种模式的相应感兴趣区域的时间-强度曲线进行了比较。结果表明，基于ICG的DCE-FI对灌注变化具有更高的敏感性，而DCE-MRI提供了上级和补充的深度相关灌注信息。应用MRI获得的深度相关灌注信息来改善术中DCE-FI的整体分析建模的研究正在进行中。
ICG-based dynamic contrast-enhanced fluorescence imaging (DCE-FI) and intraoperative DCE- magnetic resonance imaging (MRI) have been carried out nearly simultaneously in three lower extremity bone infection cases to investigate the relationship between these two imaging modalities for assessing bone blood perfusion during open orthopedic surgeries. Time-intensity curves in the corresponding regions of interest of two modalities were derived for comparison. The results demonstrated that ICG-based DCE-FI has higher sensitivity to perfusion changes while DCE-MRI provides superior and supplemental depth-related perfusion information. Research applying the depth-related perfusion information derived from MRI to improve the overall analytic modeling of intraoperative DCE-FI is ongoing.