Effects of study task on the neural correlates of source encoding
Effects of study task on the neural correlates of source encoding
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DOI：
10.1101/lm.878908
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发表时间：
2008-06-01
影响因子：
2
通讯作者：
Rugg, Michael D.
中科院分区：
文献类型：
--
作者：
Park, Heekyeong;Uncapher, Melina R.;Rugg, Michael D.
本研究探讨了源记忆的神经相关因素是否因学习任务的不同而不同。研究对象在两种背景中选择一种以视觉方式呈现单词。在每个测试中，受试者进行新旧识别和源记忆判断。在一个学习测试周期中，学习单词被要求进行动画判断，而在另一个周期中，学习任务要求进行音节判断。研究人员使用功能性磁共振成像（fMRI）来对比在随后的记忆测试中，那些能吸引准确来源判断的单词和那些来源判断不正确或来源信息不可用的单词所引发的神经活动。在这两项任务中，相对于源记忆失败的单词，后来被分配到正确来源的学习单词在腹侧纹外皮层引起了增强的活动。除了这些后续源记忆的共同影响外，还观察到对每个学习任务有选择性的额外影响。目前的研究结果增加了支持成功情景记忆编码的神经活动的建议的权重，这反映了经历事件时所进行的在线处理，以及后来的检索任务所施加的要求。
The present study investigated whether the neural correlates of source memory vary according to study task. Subjects studied visually presented words in one of two background contexts. In each test, subjects made old/new recognition and source memory judgments. In one study test cycle, study words were subjected to animacy judgments, whereas in another cycle the study task required syllable judgments. Functional magnetic resonance imaging (fMRI) was employed to contrast the neural activity elicited by study words that attracted accurate source judgments on the later memory test, as opposed to words for which source judgments were incorrect or for which source information was unavailable. In both tasks, relative to words for which source memory failed, study words that were later assigned to the correct source elicited enhanced activity in ventral extrastriate cortex. In addition to these common effects of subsequent source memory, additional effects were observed that were selective for each study task. The present findings add weight to the proposal that neural activity supporting successful episodic memory encoding is a reflection of both the online processing engaged by an episode as it is experienced, and the demands imposed by the later retrieval task.