PREVALENCE AND RISK DETERMINANTS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 (HIV-2) AND HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) IN WEST AFRICAN FEMALE PROSTITUTES
PREVALENCE AND RISK DETERMINANTS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 (HIV-2) AND HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) IN WEST AFRICAN FEMALE PROSTITUTES
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DOI：
10.1093/aje/136.7.895
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发表时间：
1992-10-01
影响因子：
5
通讯作者：
ESSEX, M
中科院分区：
文献类型：
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作者：
KANKI, P;MBOUP, S;ESSEX, M
作者研究了西非塞内加尔达喀尔（1985-1990）、齐金科尔（1987-1990）和考拉克（1987-1990）妓女中人类免疫缺陷病毒1型（HIV-1）和2型（HIV-2）的流行情况和风险决定因素。每个队列的hiv分布明显：达喀尔的HIV-2和HIV-1分别为10.0%和4.1%，齐金楚尔的HIV-2和HIV-1分别为38.1%和0.4%，考拉克的HIV-2和HIV-1分别为27.4%和1.3%。在达喀尔的1275名妓女中，性活动年数增加和有割伤史与HIV-2血清阳性相关。相比之下，HIV-1血清阳性率与较短的卖淫时间和住院史有关。在ziiguinchor的278名妓女中，HIV-2血清阳性率与几内亚比绍国籍妇女和性活动年数增加有关。在来自Kaolack的157名妓女中，HIV-2血清阳性率与性活动年数增加和从未使用安全套的历史有关。作者还研究了来自这三个地点的1280名塞内加尔妓女感染HIV-2的风险决定因素。在控制种族因素的情况下，与达喀尔地区的妇女相比，来自ziiguinchor和Kaolack的妇女更有可能是HIV-2血清阳性。性活动年数增加与HIV-2血清阳性相关，而切除史和卡介苗接种可降低HIV-2感染的风险。
The authors studied the prevalence and risk determinants for human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) in female prostitutes from Dakar (1985-1990), Ziguinchor (1987-1990), and Kaolack (1987-1990), Senegal, West Africa. Each cohort showed a distinct distribution of HIVs: 10.0% HIV-2 and 4.1% HIV-1 in Dakar, 38.1% HIV-2 and 0.4% HIV-1 in Ziguinchor, and 27.4% HIV-2 and 1.3% HIV-1 in Kaolack. in 1,275 female prostitutes from Dakar, increased years of sexual activity and a history of scarification were associated with HIV-2 seropositivity. In contrast, HIV-1 seroprevalence was associated with a shorter duration of prostitution and a history of hospitalization. In 278 female prostitutes from Ziguinchor, HIV-2 seroprevalence was associated with women of Guinea-Bissau nationality and increased years of sexual activity. In 157 female prostitutes from Kaolack, HIV-2 seroprevalence was associated with increased years of sexual activity and a history of never using condoms. The authors also studied the risk determinants for HIV-2 in the 1,280 Senegalese prostitutes pooled from all three sites. Controlling for ethnic group, women from Ziguinchor and Kaolack were more likely to be HIV-2 seropositive as compared with women from the Dakar site. Increased years of sexual activity were associated with HIV-2 seropositivity, while a history of excision and BCG vaccinations decreased the risk of HIV-2 infection.