Prognostic factors in patients who received end-of-life chemotherapy for advanced cancer
Prognostic factors in patients who received end-of-life chemotherapy for advanced cancer
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DOI：
10.1007/s10147-018-1363-7
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发表时间：
2019-04-01
影响因子：
3.3
通讯作者：
Inoue, Akira
中科院分区：
文献类型：
--
作者：
Hiramoto, Shuji;Tamaki, Tomoko;Inoue, Akira
方法回顾性分析我院2011年8月至2016年8月收治的晚期恶性肿瘤患者的临床资料。主要终点是确定末次化疗时的预后因素。结果300例评价患者中，末次化疗后14 d内死亡16例（5.3%），30 d内死亡50例（16.7%）。多因素分析显示，ECOG-PS（OR 3.698，p
Background Clinical efficacy of aggressive end-of-life (EOL) chemotherapy remains unclear.Method Medical records of patients with advanced cancer between August 2011 and August 2016 were retrospectively analyzed. The primary endpoint was to identify prognostic factors at the last administration of chemotherapy. The secondary endpoint was to analyze the relationship between EOL symptoms and EOL treatment details.Results Among 300 evaluated patients, the number of patients who died within 14 and 30 days from the last administration of chemotherapy were 16 (5.3%) and 50 (16.7%), respectively. Multivariate analysis revealed that ECOG-PS (OR 3.698, p