Initial Presentation of Type 2 Diabetes in Adolescents Predicts Durability of Successful Treatment with Metformin Monotherapy: Insights from the Pediatric Diabetes Consortium T2D Registry

Initial Presentation of Type 2 Diabetes in Adolescents Predicts Durability of Successful Treatment with Metformin Monotherapy: Insights from the Pediatric Diabetes Consortium T2D Registry
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DOI:
10.1159/000481687
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发表时间:
2018-01-01
影响因子:
3.2
通讯作者:
Beck, Roy W.
Beck, Roy W.
中科院分区:
医学3区
文献类型:
--
作者:
Bacha, Fida;Cheng, Peiyao;Beck, Roy W.

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背景/目的:许多患有 2 型糖尿病 (T2D) 的青少年在诊断后 2 年内,接受二甲双胍单药治疗后血糖控制迅速恶化。方法:使用儿科糖尿病联盟 T2D 登记处的入组数据,将 276 名 T2D 病程 >= 2 年的青少年分为两组:(1) 患有 HbA1c 的参与者
Background/Aims: Many adolescents with type 2 diabetes (T2D) have rapid deterioration of glycemic control on metformin monotherapy within 2 years of diagnosis. Methods: Enrollment data from the Pediatric Diabetes Consortium T2D Registry were used to categorize 276 youth with a T2D duration >= 2 years into two groups: (1) participants with HbA1c