Focal cortical dysplasia: Comparison of MRI and FDG-PET
Focal cortical dysplasia: Comparison of MRI and FDG-PET
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DOI：
10.1097/00004728-200003000-00022
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发表时间：
2000-03-01
影响因子：
1.3
通讯作者：
Han, BK
中科院分区：
文献类型：
--
作者：
Kim, SK;Na, DG;Han, BK
目的：目的：比较磁共振成像（MRL）和18氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）在局灶性皮质发育不良（FCD）诊断中的应用。所有患者均行MRI检查，17例患者行FDG-PET检查。结果：FCD I级4例，II级4例，III级2例。11例III级FCD患者中有9例（82%）在MRI上检测到病变，8例I级和II级FCD患者中仅1例（13%）在MRI上检测到病变。FDG-PET显示，7例I级和II级FCD患者中有6例（86%）和10例III级FCD患者中有9例（90%）的病变皮质代谢低下。17例患者中有11例（65%）FDC-PET显示的皮质异常程度大于MRI。结论：FDG-PET更有助于显示轻度FCD患者的皮质异常。与MRI相比，FDG-PET上的病变范围更大或相似。
Purpose: The purpose of this work was to compare the use of MRL and [F-18]fluorodeoxyglucose (FDG) positron emission tomography (PET) in the diagnosis of focal cortical dysplasia (FCD).Method: Nineteen patients with surgically proven FCD were analyzed retrospectively. MRI was performed in all patients, and FDG-PET was performed in 17 patients. We compared the MR and FDG-PET finding's of FCD according to the histologic findings that were classified into three grades.Results: Four cases were classified as Grade I, 4 cases as Grade II, and ii cases as Grade III FCD. The lesions were detected on MRI in 9 (82%) of the 11 patients with Grade III FCD and in only 1 (13%) of the 8 patients with Grade I and II FCD. Cortical hypometabolism of the lesion was revealed on FDG-PET in 6 (86%) of the 7 patients with Grade I and Il FCD and in 9 (90%) of the 10 patients with Grade III FCD. The extent of the cortical abnormality was larger on FDC-PET than on MRI in 11 (65%) of the 17 patients.Conclusion: FDG-PET is more useful in delineating the cortical abnormality in patients with mild degrees of FCD. The extent of the lesion was larger or similar on FDG-PET compared with that of the MRI.