Control of blood pressure and lifestyle-related risk factors in elderly Japanese hypertensive subjects.

Control of blood pressure and lifestyle-related risk factors in elderly Japanese hypertensive subjects.
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日本老年高血压受试者的血压和生活方式相关危险因素的控制。

DOI:
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发表时间:
2000
影响因子:
5.4
通讯作者:
Teruo Omae
Teruo Omae
中科院分区:
医学2区
文献类型:
--
作者:
H. Muratani;Y. Kimura;Koshiro Fukiyama;Y. Kawano;Jun Fujii;Keishi Abe;Iwao Kuwajima;Masao Ishii;Toshiaki Shiomi;Hiroshi Mikami;Setsuro Ibayashi;Teruo Omae

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本研究的目的是分析日本高血压专科医生对老年高血压患者的治疗。我们纳入了1995年在11家医院门诊接受治疗的939例高血压患者;其中793例(388例男性和405例女性;平均年龄66.6 ± 9.0岁)在1996年接受了随访检查,这些患者的数据用于本分析。分析所有患者的血压(BP)、体重指数、生活方式和实验室数据。1995年的平均血压为143+/-16/81+/-10 mmHg,1996年为142+/-15/80+/-10 mmHg。基线BP在WHO-ISH分类中处于2级或3级水平的患者(n=117)的特征是女性与男性比例较高、年龄较高、血清总胆固醇浓度较高和QRS电压较高。在这些患者中,从1995年至1996年,平均血压显着下降,而空腹血糖,血清总胆固醇和血清肌酐浓度显示只有微不足道的变化。在220名患者(28%)中,在初始和随访检查时BP <140/<90 mmHg,而1995年和1996年有351名患者(44%)患有高血压。33%的患者是吸烟者。吸烟者比非吸烟者有更多的心血管事件、糖尿病或明显的蛋白尿。总之,日本高血压专科医生治疗的患者的平均血压水平略高于WHO-ISH指南(1999)推荐的水平。应强调对患者进行教育,以控制生活方式相关的危险因素,特别是戒烟。
The aim of this study was to analyze the treatment of elderly hypertensive patients by Japanese physicians specializing in hypertension. We enrolled 939 patients with hypertension who were treated in the outpatient clinics of 11 hospitals in 1995; 793 of these patients (388 men and 405 women; mean age, 66.6+/-9.0 years) received follow-up examinations in 1996, and the data on these patients was used for the present analysis. Blood pressure (BP), body mass index, lifestyle, and laboratory data were analyzed in all patients. The average BP was 143+/-16/81+/-10 mmHg in 1995 and 142+/-15/80+/-10 mmHg in 1996. The patients whose baseline BP was at the level of Grade 2 or 3 in the WHO-ISH classification (n=117) were characterized by a higher women-to-men ratio, higher age, a higher serum total cholesterol concentration, and higher QRS voltage. In these patients, from 1995 to 1996, the average BP significantly decreased, whereas fasting plasma glucose, serum total cholesterol and serum creatinine concentrations showed only negligible changes. In 220 patients (28%), BP was <140/<90 mmHg at both the initial and the follow-up examinations, whereas 351 patients (44%) were hypertensive in both 1995 and 1996. Thirty-three percent of the patients were smokers. More smokers than nonsmokers had had prior cardiovascular events, diabetes mellitus, or overt proteinuria. In conclusion, the average BP level among the patients treated by Japanese physicians specializing in hypertension was somewhat higher than that recommended by WHO-ISH Guidelines (1999). Patient education to control lifestyle-related risk factors, particularly to stop smoking, should be emphasized.
DOI: 10.1056/nejm199904223401601
发表时间: 1999-04-22
影响因子: 158.5
作者:
Mosterd, A;D'Agostino, RB;Levy, D
通讯作者: Levy, D