Transfusions with a tan. Prevention of allosensitization by ultraviolet irradiation.
Transfusions with a tan. Prevention of allosensitization by ultraviolet irradiation.
复制标题
输血晒黑。
DOI：
10.1046/j.1537-2995.1989.29589284148.x
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发表时间：
1989
期刊：
影响因子：
2.9
通讯作者：
Deeg,HJ
中科院分区：
文献类型：
--
作者：
Deeg,HJ
对于自发性或医源性骨髓抑制或意外或医源性失血的患者，输血可作为支持性治疗。在目前的血液分型和筛查标准下，急性输血反应很少发生。当只需要一次输血或很少的输血时，通常可以获得良好的增量，并且可以提供有效的治疗。然而，对于需要反复和长期治疗的患者，输血支持，特别是血小板支持，往往变得无效，这在临床上表现为逐渐下降的恢复率和缩短的生存期。导致耐火性发展的机制可能相当复杂。然而，难治性最常见的是免疫调节。
BLOOD TRANSFUSIONS are given as supportive therapy patients suffering spontaneous or iatrogenic marrow suppression or experiencing accidental or iatrogenic blood loss. With current standards of blood typing and screening, acute transfusion reactions are infrequent. When only one transfusion or very few transfusions are required, good increments are generally achieved, and effective therapy can be provided. However, for patients who require repeated and prolonged therapy, transfusion support, in particular that with platelets, often becomes ineffective, as is evident clinically by progressively declining recovery and shortened survival. The mechanisms leading to the development of refractoriness can be quite complex. However, refractoriness is most frequently immune mediated.