See, Think, and Act: Real-Time Adaptive Radiotherapy
See, Think, and Act: Real-Time Adaptive Radiotherapy
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DOI：
10.1016/j.semradonc.2019.02.005
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发表时间：
2019-07-01
影响因子：
3.5
通讯作者：
Booth, Jeremy T.
中科院分区：
文献类型：
--
作者：
Keall, Paul;Poulsen, Per;Booth, Jeremy T.
世界正在拥抱信息时代，实时数据可以帮助做出许多决策。同样，在癌症放射治疗中，我们正坚定不移地以更智能、更快速的方式使用信息，以迎来实时自适应放射治疗的时代。与无人驾驶车辆技术相结合的实时自适应放射治疗的三个关键步骤是连续的观察、思考和行动循环。请参阅：使用成像系统来探测患者随时间变化的解剖结构或生理结构。思考：利用当前和先前的信息，利用可用的自适应自由度来优化治疗。行动：提供实时适应的治疗。本文扩展了实时自适应放射治疗的这三个关键步骤，提供了历史背景，回顾了临床原理，并给出了实时自适应放射治疗的未来展望。 (C) 2019 Elsevier Inc. 保留所有权利。
The world is embracing the information age, with real-time data at hand to assist with many decisions. Similarly, in cancer radiotherapy we are inexorably moving toward using information in a smarter and faster fashion, to usher in the age of real-time adaptive radiotherapy. The three critical steps of real-time adaptive radiotherapy, aligned with driverless vehicle technology are a continuous see, think, and act loop. See: use imaging systems to probe the patient anatomy or physiology as it evolves with time. Think: use current and prior information to optimize the treatment using the available adaptive degrees of freedom. Act: deliver the real-time adapted treatment. This paper expands upon these three critical steps for real-time adaptive radiotherapy, provides a historical context, reviews the clinical rationale, and gives a future outlook for real-time adaptive radiotherapy. (C) 2019 Elsevier Inc. All rights reserved.