The connectivity of the superior longitudinal fasciculus: a tractography DTI study
The connectivity of the superior longitudinal fasciculus: a tractography DTI study
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DOI：
10.1016/j.mri.2009.07.008
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发表时间：
2010-02-01
影响因子：
2.5
通讯作者：
Altman, Nolan
中科院分区：
文献类型：
--
作者：
Bernal, Byron;Altman, Nolan
目的：左上纵束被认为是连接语言接受区和语言表达区。后者位于左侧额下健身房的包部（布罗卡区）。我们报告了一组正常志愿者的单侧颞叶牵引道造影结果。方法与材料：对12名参加机构审查委员会批准的扩散张量成像研究的正常右撇子志愿者的数据和辅助结果进行评估。SLF纤维是双侧获得的，在每个皮质脊髓束外侧的三角形区域放置一个感兴趣的区域，在昏迷胼胝体的冠状面上。矢状分数各向异性图像用于确定与特定脑回或额叶部分有关的白质中SLF纤维的吻侧端点。SLF对Broca区的投影定性为无、最小、大部分或全部。调查结果以描述性统计的形式呈现。结果：7例（58.3%）无SLF向Broca区投射，5例（41.6%）有SLF向Broca区投射。在100%的病例中，SLF的吻侧终点唯一或主要出现在中央前回。结论：发现SLF连接后部语言区和中央前回，在某些情况下仅少量连接典型的Broca区。这一发现与描述SLF侧化与语言区域之间缺乏相关性的报告一致。对语言回路的理解随着语言轨迹描记术的使用而开始出现。(C) 2010爱思唯尔公司版权所有。
Purpose: The left superior longitudinal fasciculus (SLF) has been felt to link receptive with expressive language areas. The latter is located in the pars opercularis (Broca's area) of the left inferior frontal gyms. We report the findings with tractography of the SLF in a group of normal volunteers.Methods and materials: The data and subsidiary results of 12 normal right-handed volunteers who participated in an institutional review board-approved diffusion tensor imaging study were evaluated. The SLF fibers were obtained bilaterally placing a region of interest at the triangular-shaped region lateral to each of the corticospinal tracts, in a coronal plane along the rostra] aspect of the comas callosum. A sagittal fractional anisotropy image was used to determine the rostral endpoint of the SLF fibers in the white matter pertaining to specific gyri or pars of the frontal lobe. The SLF projection to Broca's area was ranked qualitatively as none, minimal, most or all. Findings are presented in descriptive statistics.Results: The SLF projection to Broca's areas was absent in seven subjects (58.3%) and minimal in five (41.6%). SLF's rostral end points were found uniquely or mainly in the precentral gyros in 100% of cases.Conclusion: The SLF was found connecting the posterior language areas to the precentral gyrus and only marginally in some cases to the canonical Broca's area. This finding is consistent with reports describing lack of correlation between lateralization of the SLF and language areas. The understanding of language circuitry is beginning to emerge with the use of tractography. (C) 2010 Elsevier Inc. All rights reserved.