COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals.

COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals.
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DOI:
10.1016/j.pan.2021.04.005
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发表时间:
2021-04-20
期刊:
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
影响因子:
--
通讯作者:
Goggins M
Goggins M
中科院分区:
其他
文献类型:
--
作者:
Katona BW;Mahmud N;Dbouk M;Ahmad N;Chhoda A;Dudley B;Hayat U;Kwon RS;Lee LS;Rustgi AK;Ukaegbu C;Vasquez L;Volk S;Brand RE;Canto MI;Chak A;Farrell JJ;Kastrinos F;Stoffel EM;Syngal S;Goggins M

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COVID-19 pandemic-related disruptions to EUS-based pancreatic cancer surveillance in high-risk individuals remain uncertain. Analysis of enrolled participants in the CAPS5 Study, a prospective multicenter study of pancreatic cancer surveillance in high-risk individuals. Amongst 693 enrolled high-risk individuals under active surveillance, 108 (16%) had an EUS scheduled during the COVID-19 pandemic-related shutdown (median length of 78 days) in the spring of 2020, with 97% of these procedures being canceled. Of these canceled surveillance EUSs, 83% were rescheduled in a median of 4.1 months, however 17% were not rescheduled after 6 months follow-up. Prior history of cancer was associated with increased likelihood of rescheduling. To date no pancreatic cancer has been diagnosed among those whose surveillance was delayed. COVID-19 delayed pancreatic cancer surveillance with no adverse outcomes in efficiently rescheduled individuals. However, 1 in 6 high-risk individuals had not rescheduled surveillance, indicating the need for vigilance to ensure timely surveillance rescheduling.
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