How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory
How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory
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DOI：
10.1016/j.diagmicrobio.2020.115123
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发表时间：
2020-10-01
影响因子：
2.9
通讯作者：
Ren, Ping
中科院分区：
文献类型：
--
作者：
Thwe, Phyu M.;Ren, Ping
本文回顾性分析了182对干鼻咽拭子经Abbott ID NOW检测和鼻咽拭子经病毒转运培养基实时荧光定量PCR检测的对比结果。虽然总体一致性为96.2%，但我们发现，在RT-PCR方法检测为阳性的15个样本中，有7个被ID NOW遗漏，导致假阴性率为47%。(C)2020爱思唯尔公司All rights reserved.
Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47%. (C) 2020 Elsevier Inc. All rights reserved.