Association Between BMI and Recurrence of Primary Spontaneous Pneumothorax.
Association Between BMI and Recurrence of Primary Spontaneous Pneumothorax.
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BMI 与原发性自发性气胸复发的关系
DOI：
10.1007/s00268-016-3848-8
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发表时间：
2017-05
影响因子：
2.6
通讯作者：
Yang N
中科院分区：
文献类型：
--
作者：
Tan J;Yang Y;Zhong J;Zuo C;Tang H;Zhao H;Zeng G;Zhang J;Guo J;Yang N
摘要背景体重指数(BMI)是否是原发性自发性气胸(PSP)复发的重要危险因素仍存在争议。这项研究的目的是检验BMI和其他因素是否与PSP复发风险有关。方法对273名患者进行连续队列回顾评估。将患者分为复发组(n=81)和未复发组(n=192)，以及低BMI组(n=75)和正常或高BMI组(n=198)。结果273例患者1年复发率为20.9%，2年复发率为23.8%，5年复发率为28.7%。单变量分析确定了以下显著预测PSP复发的因素：身高、体重、BMI、气胸大小和治疗方式。多变量分析确定了几个导致PSP复发的危险因素：低体重指数、气胸大小≥为50%以及非手术治疗。Kaplan-Meier生存分析显示，低体重指数患者的无复发生存率显著低于体重指数正常或增高者(P<；0.001)。结论低体重指数、气胸大小≥为50%、非手术治疗是本组病例中PSP复发的危险因素。低BMI可能是PSP复发的一个临床有用的预测指标。
AbstractBackgroundWhether body mass index (BMI) is a significant risk factor for recurrence of primary spontaneous pneumothorax (PSP) remains controversial. The purpose of this study was to examine whether BMI and other factors are linked to risk of PSP recurrence.MethodsA consecutive cohort of 273 patients was retrospectively evaluated. Patients were divided into those who experienced recurrence (n= 81) and those who did not (n= 192), as well as into those who had low BMI (n= 75) and those who had normal or elevated BMI (n= 198). The two pairs of groups were compared in terms of baseline data, and Cox proportional hazards modeling was used to identify predictors of PSP recurrence.ResultsRates of recurrence among all 273 patients were 20.9% at 1 year, 23.8% at 2 years, and 28.7% at 5 years. Univariate analysis identified the following significant predictors of PSP recurrence: height, weight, BMI, size of pneumothorax, and treatment modality. Multivariate analyses identified several risk factors for PSP recurrence: low BMI, pneumothorax size ≥50%, and non‐surgical treatment. Kaplan–Meier survival analysis indicated that patients with low BMI showed significantly lower recurrence‐free survival than patients with normal or elevated BMI (P< 0.001).ConclusionsLow BMI, pneumothorax size ≥50%, and non‐surgical treatment were risk factors for PSP recurrence in our cohort. Low BMI may be a clinically useful predictor of PSP recurrence.