On the status of object concepts in aphasia
On the status of object concepts in aphasia
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DOI：
10.1006/brln.1997.1771
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发表时间：
1997-06-15
影响因子：
2.5
通讯作者：
Whitehead, V
中科院分区：
文献类型：
--
作者：
Chertkow, H;Bub, D;Whitehead, V
虽然失语症患者的语言理解能力常常因左半球损伤而受损，但关于物体的非语言概念知识的地位仍存在争议。我们测试了16名失语症患者对具体单词的理解。当干扰词是语义上的，而不仅仅是感知上的混淆时，8个词对图片匹配有明显的损害。这8个人在回答关于相同项目的口头调查问题时也犯了错误。然而，当测试相同的探测问题的非语言图片版本，这8个改善他们的表现正常对照组的水平。其他5个表现出持续的损害，在指示图像探针的反应。这5个没有表现出普遍的智力障碍的证据，它的结论是，他们表现出理解缺陷不仅限于语言领域。与其他失语症患者不同，后5例患者的CT扫描病变也延伸到左颞叶后部（涉及Brodmann区22、21和37）。他们在一般性失语症的严重程度方面也受到更多的损害。有人建议，一个非语言（以及言语）语义记忆缺陷发生在一个亚组的患者与单个单词的理解障碍，由于失语症，这可能反映了语言障碍的一般严重程度，以及某些局部脑区的损害。(C)北京：科学出版社.
While verbal comprehension is often impaired in aphasia due to left hemispheric damage, the status of nonverbal conceptual knowledge of objects remains controversial. We tested 16 aphasic subjects for their comprehension of concrete single words. Eight showed significant impairment on word-to-picture matching, when distracters were semantically and not just perceptually confusable. These 8 also made errors in answering verbal probe questions concerning the same items. When tested on a nonverbal pictorial version of the same probe questions, however, 3 of these 8 improved their performance to the level of normal controls. The other 5 showed continuing impairment in indicating responses to pictorial probes. These 5 showed no evidence of generalized intellectual impairment, and it is concluded that they demonstrated a comprehension deficit not limited to the verbal domain. Unlike the other aphasic patients, these latter 5 also had CT scan lesions extending into the posterior left temporal lobe (involving Brodmann's areas 22, 21, and 37). They were also more impaired in terms of general aphasia severity. It is suggested that a nonverbal (as well as verbal) semantic memory deficit occurs in a subgroup of patients with single word comprehension disturbance due to aphasia, and this may reflect general severity of language impairment as well as damage to certain localized brain regions. (C) 1997 Academic Press.