Environmentally Responsive Core/Shell Particles via Electrohydrodynamic Co-jetting of Fully Miscible Polymer Solutions
Environmentally Responsive Core/Shell Particles via Electrohydrodynamic Co-jetting of Fully Miscible Polymer Solutions
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DOI：
10.1002/smll.200800565
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发表时间：
2008-10-01
期刊：
影响因子：
13.3
通讯作者：
Lahann, Joerg
中科院分区：
文献类型：
--
作者：
Kazemi, Abbass;Lahann, Joerg
本文证明电流体动力共喷射不仅限于Janus型颗粒，还可以用于制备核/壳颗粒。利用可混溶聚合物溶液的并排流动，电流体动力共喷射提供了一种优雅且可扩展的途径，用于制备具有其他难以制备的颗粒结构的核/壳颗粒，包括具有亲水壳和核的颗粒。在整个研究中，使用了由 PAAm-co-AA 和 PAA 混合物组成的水溶液的电流体动力学共喷射，并观察到一系列具有不同隔室的不同类型的颗粒。从 Janus 颗粒到核/壳颗粒的转变似乎是由两种喷射溶液的相对电导率的变化引起的。交联后，核/壳颗粒在水溶液中稳定，并表现出可重复的溶胀行为，同时保持原始的核/壳几何形状。此外，通过在 1.3 和 12 之间反复切换环境 pH 值，证明了颗粒的 pH 响应性。此外，核/壳颗粒显示出令人惊讶的吸收选择性。例如，发现 6-羧基荧光素的吸收比罗丹明 B 碱增加了 450%。
Herein it is demonstrated that electrohydrodynamic co-jetting is not limited to Janus-type particles, but can also be used for the preparation of core/shell particles. Using side-by-side flow of miscible polymer solutions, electrohydrodynamic co-jetting offers an elegant and scalable route towards preparation of core/shell particles with otherwise difficult-to-prepare particle architectures, including particles with hydrophilic shell and core. Throughout this study, electrohydrodynamic co-jetting of aqueous solutions consisting of a mixture of PAAm-co-AA and PAA is used, and a range of different types of particles with distinct compartments are observed. Transition from Janus particles to core/shell particles appears to be caused by changes in the relative conductivity of the two jetting solutions. After crosslinking, the core/shell particles are stable in aqueous solution and exhibit reproducible swelling behavior while maintaining the original core/shell geometry. In addition, the pH-responsiveness of the particles is demonstrated by repeatedly switching the environmental pH between 1.3 and 12. Moreover, the core/shell particles show surprising uptake selectivity. For instance, a 450% increase in uptake of 6-carboxyfluorescein over rhodamine B base is found.