Sequence of the mitochondrial genome of Pneumocystis carinii: implications for biological function and identification of potential drug targets.
Sequence of the mitochondrial genome of Pneumocystis carinii: implications for biological function and identification of potential drug targets.
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卡氏肺孢子虫线粒体基因组序列：对生物功能和潜在药物靶标识别的影响。
DOI：
10.1111/j.1550-7408.2006.00212.x
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Smulian,AGeorge
中科院分区：
文献类型：
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作者：
Sesterhenn,ThomasM;Cushion,MelanieT;Slaven,BradleyE;Smulian,AGeorge
本文介绍了一项研究，组装线粒体序列的卡氏肺孢子虫，导致肺孢子虫基因组计划。这种组装将有助于这些基因的转录分析及其对已知和实验性疗法的反应。也可能推断出真菌王国的其他成员与卡氏肺孢子虫之间的进化关系。
The article presents a study that assembles mitochondrial sequences of Pneumocystis carinii, resulting from the Pneumocystis Genome Project. Such assembly will facilitate the transcriptional analysis of these genes and their responses to known and experimental therapies. It may also be possible to deduce evolutionary relationships between other members of the fungal kingdom and Pneumocystis carinii.