Effect of Maltose and Diet Containing Starch on Maltitol Hydrolysis in Rat
Effect of Maltose and Diet Containing Starch on Maltitol Hydrolysis in Rat
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麦芽糖和含淀粉饲料对大鼠麦芽糖醇水解的影响
DOI：
10.4327/jsnfs1949.34.2_145
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
N. Hosoya
中科院分区：
文献类型：
--
作者：
T. Oku;Soon Hi Him;N. Hosoya
以大鼠小肠粘膜为材料，研究了麦芽糖醇水解酶的活性、定位及麦芽糖对麦芽糖醇水解的影响。此外，在禁食和进食大鼠中观察到麦芽糖醇的利用。主要研究结果如下：1.空肠中麦芽糖醇的水解活性最高，约为麦芽糖的二十分之一.麦芽糖对空肠酶水解麦芽糖醇有强烈的抑制作用.麦芽糖醇被麦芽糖酶缓慢水解.当动物同时给予麦芽糖醇和饲料时，与单独给予麦芽糖醇相比，麦芽糖醇的利用率显著降低.给药的一部分麦芽糖醇在肠道中吸收而不水解，天然形式麦芽糖醇经尿液排泄。
The activity and localization of hydrolysis enzyme of maltitol and the effect of maltose on maltitol hydrolysis were studied using the rat intestinal mucosa. The utilization of maltitol was, further, observed in the fasted and in the fed rats. The results obtained were as follows:1. The hydrolysis activity to maltitol was highest in the jejunum and was about one-twentieth of that to maltose.2. The maltitol hydrolysis by jejunal enzyme was strongly inhibited in the presence of maltose.3. It was suggested that maltitol was slowly hydrolyzed by maltase.4. When the animal was simultaneously given with maltitol and diet, the utilization of maltitol was significantly reduced as compared with that of the dose of maltitol alone.5. A portion of maltitol administered was absorbed without hydrolysis from intestine, and the native form, maltitol, was excreted in the urine.