LINKAGE OF A GENE FOR DOMINANT NON-SYNDROMIC DEAFNESS TO CHROMOSOME-19
LINKAGE OF A GENE FOR DOMINANT NON-SYNDROMIC DEAFNESS TO CHROMOSOME-19
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DOI：
10.1093/hmg/4.6.1073
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发表时间：
1995-06-01
影响因子：
3.5
通讯作者：
SMITH, RJH
中科院分区：
文献类型：
--
作者：
CHEN, AH;NI, L;SMITH, RJH
遗传性听力损伤既可发生在伴有其他临床特征的综合征性听力损失（syndromic hearing loss，SHL）中，也可发生在单独的非综合征性听力损失（non-syndromic hearing loss，NSHL）中，后者更为常见且具有高度异质性。迄今为止，已定位了6个NSHL基因座。
Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL), The latter is more common and is highly heterogeneous, To date, six NSHL loci have been mapped, We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.