Risk factors for work disability in severe adult asthma
Risk factors for work disability in severe adult asthma
复制标题
DOI：
10.1016/j.amjmed.2006.01.016
复制
发表时间：
2006-10-01
影响因子：
5.9
通讯作者：
Blanc, Paul D.
中科院分区：
文献类型：
--
作者：
Eisner, Mark D.;Yelin, Edward H.;Blanc, Paul D.
目的：我们旨在阐明严重成人哮喘中工作残疾的患病率和危险因素，并评估工作残疾对下游健康结果的影响。方法：我们使用了一项对 465 名成人严重哮喘患者进行前瞻性队列研究的数据。结构化电话访谈确定了哮喘状况和就业史。工作暴露矩阵 (JEM) 用于描述工作场所接触“哮喘原”的可能性。 结果：在患有严重哮喘的工作年龄成人中，与哮喘相关的完全工作残疾的患病率为 14%（95% 置信区间，11%-18%）。在目前就业的人中，部分工作残疾的患病率为 38%（95% 置信区间，31%-45%）。社会人口统计学 (P=.027) 和医疗因素 (P=.020) 与完全丧失工作能力的风险相关。社会人口特征 (P=.06) 和基于 JEM 的工作暴露 (P=.012) 都与部分工作残疾有关。在其他模型中，较差的哮喘严重程度、身体健康状况和心理健康状况都与完全和部分工作残疾的风险较高相关。结论：工作残疾在患有严重哮喘的成年人中很常见。工作残疾的三组风险因素是可以改变的：吸烟、工作场所暴露和哮喘严重程度。 (c) 2006 Elsevier Inc. 保留所有权利。
PURPOSE: We aimed to elucidate the prevalence of and risk factors for work disability in severe adult asthma and to evaluate the impact of work disability on downstream health outcomes.METHODS: We used data from a prospective cohort study of 465 adults with severe asthma. Structured telephone interviews ascertained asthma status and employment history. A job exposure matrix (JEM) was used to characterize the likelihood of workplace exposure to "asthmagens."RESULTS: The prevalence of asthma-related complete work disability was 14% among working-age adults with severe asthma (95% confidence interval, 11%-18%). Among those who were currently employed, the prevalence of partial work disability was 38% ( 95% confidence interval, 31%-45%). Sociodemographic (P=.027) and medical factors (P=.020) were related to the risk of complete work disability. Both sociodemographic characteristics (P=.06) and work exposures based on the JEM (P=.012) were related to partial work disability. In additional models, poorer asthma severity, physical health status, and mental health status were all associated with a higher risk of complete and partial work disability.CONCLUSIONS: Work disability is common among adults with severe asthma. There are three sets of risk factors for work disability that are potentially modifiable: smoking, workplace exposures, and asthma severity. (c) 2006 Elsevier Inc. All rights reserved.