Microwave tissue ablation: biophysics, technology, and applications.
Microwave tissue ablation: biophysics, technology, and applications.
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DOI：
10.1615/critrevbiomedeng.v38.i1.60
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发表时间：
2010
影响因子：
--
通讯作者：
Brace CL
中科院分区：
文献类型：
--
作者：
Brace CL
微波消融术是许多癌症、心律失常和其他疾病的新兴治疗选择。在治疗过程中，微波直接作用于组织，使温度迅速升高，足以产生立即凝固性坏死。每种应用程序的工程设计标准不同，需要考虑诸如所需消融区大小、治疗持续时间和程序侵入性等因素。应用冷却、功率控制和特定应用系统优化方面的最新技术发展有望在未来提高微波烧蚀的利用率。本文综述了微波组织加热的基本生物物理学，概述了现有设备的设计和运行，并概述了微波消融的未来研究领域。
Microwave ablation is an emerging treatment option for many cancers, cardiac arrhythmias and other medical conditions. During treatment, microwaves are applied directly to tissues to produce rapid temperature elevations sufficient to produce immediate coagulative necrosis. The engineering design criteria for each application differ, with individual consideration for factors such as desired ablation zone size, treatment duration, and procedural invasiveness. Recent technological developments in applicator cooling, power control and system optimization for specific applications promise to increase the utilization of microwave ablation in the future. This article will review the basic biophysics of microwave tissue heating, provide an overview of the design and operation of current equipment, and outline areas for future research for microwave ablation.