Accuracy of self-reported breast cancer among women undergoing mammography.
Accuracy of self-reported breast cancer among women undergoing mammography.
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DOI：
10.1007/s10549-009-0375-4
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发表时间：
2009-12
影响因子：
3.8
通讯作者：
Miglioretti, Diana L.
中科院分区：
文献类型：
--
作者：
Abraham, Linn;Geller, Berta M.;Yankaskas, Bonnie C.;Bowles, Erin J. A.;Karliner, Leah S.;Taplin, Stephen H.;Miglioretti, Diana L.
本研究使用乳腺癌监测联盟的数据评估了自我报告的乳腺癌的敏感性和特异性及其与患者因素和病理结果的相关性。我们纳入了24，631名先前诊断为乳腺癌的女性和463，804名先前未诊断为乳腺癌的女性，这些女性在1996年至2006年期间在参与美国乳房X光检查的机构完成了问卷调查（包括乳腺癌病史）。我们使用癌症登记和病理学数据库确定了“真实”癌症状态。多变量逻辑回归模型被用来检查与患者因素和病理结果的关联。浸润性癌女性自我报告乳腺癌的敏感性（96.9%）高于导管原位癌（DCIS）（90.2%）。总体特异性较高（99.7%），但有小叶原位癌（LCIS）病史的女性特异性较低（65.0%）。在多变量模型中，报告年龄较大，非白人种族/民族或教育程度较低的女性的敏感性和特异性较低。当存在既往DCIS的证据时，敏感性降低，特别是在完成问卷调查前2年以上做出诊断时。有乳腺癌家族史的女性敏感性更高。既往LCIS的证据与较低的特异性相关。自我报告的乳腺癌的准确性取决于受访者的特征和先前的诊断。非白人妇女和报告受教育程度较低的妇女的准确性较低。乳腺癌的发现，如DCIS和LCIS，似乎存在不确定性。这些结果对依赖自我报告的研究以及患者沟通和护理具有重要意义。
This study estimated the sensitivity and specificity of self-reported breast cancer and their associations with patient factors and pathologic findings using data from the Breast Cancer Surveillance Consortium. We included 24,631 women with and 463,804 women without a prior diagnosis of breast cancer who completed a questionnaire (including breast cancer history) at participating U.S. mammography facilities between 1996 and 2006. We determined “true” cancer status using cancer registries and pathology databases. Multivariable logistic regression models were used to examine associations with patient factors and pathologic findings. Sensitivity of self-reported breast cancer was higher for women with invasive cancer (96.9%) than for those with ductal carcinoma in situ (DCIS) (90.2%). Specificity was high overall (99.7%) but much lower for women with a history of lobular carcinoma in situ (LCIS) (65.0%). In multivariable models, women reporting older ages, a nonwhite race/ethnicity, or less education had lower sensitivities and specificities. Sensitivity was reduced when there was evidence of prior DCIS, especially when this diagnosis had been made more than 2 years before questionnaire completion. Women reporting a family history of breast cancer had higher sensitivity. Evidence of prior LCIS was associated with lower specificity. The accuracy of self-reported breast cancer depends on the respondent’s characteristics and prior diagnoses. Accuracy is lower among nonwhite women and women reporting less education. There appears to be uncertainty surrounding breast findings such as DCIS and LCIS. These results have important implications for research relying on self-report and for patient communication and care.
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影响因子：
5
作者：
Desai, MM;Bruce, ML;Druss, BG
通讯作者：
Druss, BG
影响因子：
10.3
作者：
Barlow, William E.;White, Emily;Kerlikowske, Karla
通讯作者：
Kerlikowske, Karla
影响因子：
2.3
作者：
Cronin, KA;Yu, BB;Feuer, EJ
通讯作者：
Feuer, EJ
影响因子：
158.5
作者：
Elmore, G;Barton, MB;Fletcher, SW
通讯作者：
Fletcher, SW
影响因子：
5.1
作者：
Kerner, JF;Yedidia, M;Mandelblatt, JS
通讯作者：
Mandelblatt, JS