A novel, low cost, disposable, pediatric pulsatile rotary ventricular pump for cardiac surgery that provides a physiological flow pattern.
A novel, low cost, disposable, pediatric pulsatile rotary ventricular pump for cardiac surgery that provides a physiological flow pattern.
复制标题
一种新型、低成本、一次性儿科脉动旋转心室泵，用于心脏手术，提供生理流动模式。
DOI：
10.1097/mat.0b013e3181870a6d
复制
发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Merz,ScottI
中科院分区：
文献类型：
--
作者：
Mazur,DanielE;Osterholzer,KathrynR;Toomasian,JohnM;Merz,ScottI
目前正在研究开发一种用于心脏手术的新型、低成本、一次性儿科搏动旋转心室泵（PRVP），该泵可提供生理流动模式。这被认为可以降低该人群的发病率和风险暴露。PRVP具有耐用设计，适用于术后短至中等长度的长时间支撑，无需更换泵。该设计基于专有的MC 3技术，可提供每次冲程的可变泵送量，从而使泵能够响应患者的血液动力学状态变化。新型泵设计还具有安全优势，可防止逆流，并在入口和出口管路堵塞时保持安全回路压力。该设计是简单、安全和自然的流量支持的理想选择。已经开发出预测不同几何形状的泵室的输出的计算方法。对缩放腔室和泵头（直径= 4 in）进行原型设计，以证明儿科的目标性能（100 rpm时2 L/min）。开发了一种在恒定RPM下产生脉动流和压力输出的新方法，并证明其在简化的模拟患者回路中产生显著的剩余液压能（> 10%）。
Research is underway to develop a novel, low cost, disposable pediatric pulsatile rotary ventricular pump (PRVP) for cardiac surgery that provides a physiological flow pattern. This is believed to offer reduced morbidity and risk exposure within this population. The PRVP will have a durable design suitable for use in short-to mid-length prolonged support after surgery without changing pumps. The design is based on proprietary MC3 technology which provides variable pumping volume per stroke, thereby allowing the pump to respond to hemodynamic status changes of the patient. The novel pump design also possesses safety advantages that prevent retrograde flow, and maintain safe circuit pressures upon occlusion of the inlet and outlet tubing. The design is ideal for simple, safe and natural flow support. Computational methods have been developed that predict output for pump chambers of varying geometry. A scaled chamber and pump head (diameter= 4 in) were prototyped to demonstrate target performance for pediatrics (2 L/min at 100 rpm). A novel means of creating a pulsatile flow and pressure output at constant RPM was developed and demonstrated to create significant surplus hydraulic energy (> 10%) in a simplified mock patient circuit.