Mirror movements in healthy humans across the lifespan: effects of development and ageing
Mirror movements in healthy humans across the lifespan: effects of development and ageing
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DOI：
10.1111/j.1469-8749.2010.03766.x
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发表时间：
2010-12-01
影响因子：
3.8
通讯作者：
Danek, Adrian
中科院分区：
文献类型：
--
作者：
Koerte, Inga;Eftimov, Lara;Danek, Adrian
目的镜像运动是儿童时期的一种短暂现象，随着运动发育，其强度逐渐减弱。抑制能力的增强导致运动偏侧化的能力被认为是其机制。我们的目的是量化意外的镜子运动系统的寿命和调查的影响，年龄，性别，用手，和任务frequency.METHOD共236名参与者（127名女性，109名男性; 216右撇子，20左撇子;年龄范围3- 96岁，中位数25岁8个月）首先进行了四个临床常规测试，而镜子运动被评为观察员。然后，他们被要求在每只手之间的拇指和食指，并执行振荡的握力变化，在一只手，而另一只手，以防止力传感器dropping.Results年龄表现出很强的非线性效应的镜子运动比（镜子和主动手的振幅比，调整各自的最大握力）。最初，在儿童和青少年时期，镜像运动比率急剧下降，随后在成年期逐渐上升。男性的镜像运动比率低于女性。高频率条件触发较低的反射镜运动比率。优势和非优势的手，或左，右利手的参与者之间的镜像运动没有显着差异，被发现。解释这项研究提供了，第一次我们的知识，规范值的镜像运动的整个生命周期，可以帮助区分生理和病理镜像运动。
AIM Mirror movements are a transient phenomenon during childhood, which decrease in intensity with motor development. An increasing inhibitory competence resulting in the ability of movement lateralization is thought to be the underlying mechanism. We aimed to quantify unintended mirror movements systematically across the lifespan and to investigate the influences of age, sex, handedness, and task frequency.METHOD A total of 236 participants (127 females, 109 males; 216 right-handed, 20 left-handed; age range 3-96y, median 25y 8mo) first performed four clinical routine tests while mirror movements were rated by the observer. They were then asked to hold a force transducer in each hand between the thumb and index finger and to perform oscillatory grip force changes in one hand, while the other hand had to prevent the force transducer from dropping.RESULTS Age showed a strong nonlinear effect on the mirror-movement ratio (the amplitude ratio of the mirror and active hand, adjusted by the respective maximum grip force). Initially, there was a steep decline in the mirror-movement ratio during childhood and adolescence, followed by a gradual rise during adulthood. Males had lower mirror-movement ratios than females. The high-frequency condition triggered lower mirror-movement ratios. No significant differences of mirror movements between dominant and non-dominant hand, or left-and right-handed participants, were found.INTERPRETATION This study provides, for the first time to our knowledge, normative values of mirror movements across the lifespan that can aid differentiation between physiological and pathological mirror movements.