Association of maternal stature with offspring mortality, underweight, and stunting in low- to middle-income countries.
Association of maternal stature with offspring mortality, underweight, and stunting in low- to middle-income countries.
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DOI：
10.1001/jama.2010.450
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发表时间：
2010-04-21
影响因子：
120.7
通讯作者：
Subramanian, S. V.
中科院分区：
文献类型：
--
作者：
Ozaltin, Emre;Hill, Kenneth;Subramanian, S. V.
尽管母亲的身高与后代死亡率和健康有关，但这种关系在发展中国家普遍存在的程度尚不清楚。在54个低收入到中等收入国家中，研究母亲身高与婴儿死亡率、体重不足、发育迟缓和婴幼儿早期消瘦之间的关系。分析了1991年至2008年间在54个国家进行的109项人口与健康调查。研究人群包括具有全国代表性的0至59个月儿童的横断面样本，这些儿童的母亲年龄在15岁至49岁之间。样本大小分别为2661519(死亡率)、587096(体重不足)、558347(发育迟缓)和568609(消瘦)。5岁以下儿童死亡、体重不足、发育迟缓或消瘦的可能性。死亡率数据集中所有调查的平均应答率为92.8%。在调整后的模型中，母亲身高增加1厘米与儿童死亡率(绝对风险差，0.0014；相对风险[RR]，0.988；95%可信区间[CI]，0.987-0.988)、体重不足(ARD，0.0068；RR，0.968；95%CI，0.968-0.969)、发育迟缓(ARD，0.0126；RR，0.968；95%CI，0.967-0.968)和消瘦(ARD，0.0005；RR，0.994；95%可信区间，0.993-0.995)。身高最高的母亲所生的孩子死亡的绝对风险为0.073(95%CI，0.072-0.074)，而身高最矮的母亲所生的孩子死亡的绝对风险为0.128(95%CI，0.126-0.130)。与母亲身高增加1厘米相关的儿童死亡风险因国家而异的下降幅度在0.978至1.011之间，54个国家中有46个国家(85%)的风险下降具有统计学意义(α=0.05)。在54个低收入到中等收入国家中，母亲的身高与婴儿和儿童时期的后代死亡率、体重不足和发育迟缓呈负相关。
Although maternal stature has been associated with offspring mortality and health, the extent to which this association is universal across developing countries is unclear. To examine the association between maternal stature and offspring mortality, underweight, stunting, and wasting in infancy and early childhood in 54 low- to middle-income countries. Analysis of 109 Demographic and Health Surveys in 54 countries conducted between 1991 and 2008. Study population consisted of a nationally representative cross-sectional sample of children aged 0 to 59 months born to mothers aged 15 to 49 years. Sample sizes were 2 661 519 (mortality), 587 096 (underweight), 558 347 (stunting), and 568 609 (wasting) children. Likelihood of mortality, underweight, stunting, or wasting in children younger than 5 years. The mean response rate across surveys in the mortality data set was 92.8%. In adjusted models, a 1-cm increase in maternal height was associated with a decreased risk of child mortality (absolute risk difference [ARD], 0.0014; relative risk [RR], 0.988; 95% confidence interval [CI], 0.987–0.988), underweight (ARD, 0.0068; RR, 0.968; 95% CI, 0.968–0.969), stunting (ARD, 0.0126; RR, 0.968; 95% CI, 0.967–0.968), and wasting (ARD, 0.0005; RR, 0.994; 95% CI, 0.993–0.995). Absolute risk of dying among children born to the tallest mothers (≥160 cm) was 0.073 (95% CI, 0.072–0.074) and to those born to the shortest mothers (<145 cm) was 0.128 (95% CI, 0.126–0.130). Country-specific decrease in the risk for child mortality associated with a 1-cm increase in maternal height varied between 0.978 and 1.011, with the decreased risk being statistically significant in 46 of 54 countries (85%) (α=.05). Among 54 low- to middle-income countries, maternal stature was inversely associated with offspring mortality, underweight, and stunting in infancy and childhood.
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影响因子：
2.8
作者：
FRISANCH.AR;SANCHEZ, J;YANEZ, L
通讯作者：
YANEZ, L
影响因子：
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