Neuroanatomical correlates of anticipatory anxiety.
Neuroanatomical correlates of anticipatory anxiety.
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预期焦虑的神经解剖学相关性。
DOI：
10.1126/science.2784226
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Raichle,ME
中科院分区：
文献类型：
--
作者：
Reiman,EM;Fusselman,MJ;Fox,PT;Raichle,ME
正电子发射断层扫描测量局部血流量，局部神经元活动的标志，被用来研究神经解剖学相关的正常情绪。研究人员对健康志愿者进行了电击前、电击中和电击后的研究。在预期焦虑期间，双侧颞极的血流量显著增加，最近在惊恐障碍患者中涉及乳酸盐诱导的焦虑发作的相同区域。因此，颞极似乎与人类焦虑的正常和病理形式有关。
Positron emission tomographic measurements of regional blood flow, a marker of local neuronal activity, were used to investigate the neuroanatomical correlates of a normal emotion. Healthy volunteers were studied before, during, and after anticipation of a painful electric shock. During anticipatory anxiety, there were significant blood flow increases in bilateral temporal poles, the same regions recently implicated in a lactate-induced anxiety attack in patients with panic disorder. Thus, the temporal poles seem to be involved in normal and pathological forms of human anxiety.