Quantitative breath-hold monitoring of myocardial gadolinium enhancement using inversion recovery TrueFISP

Quantitative breath-hold monitoring of myocardial gadolinium enhancement using inversion recovery TrueFISP
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DOI:
10.1002/mrm.20369
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发表时间:
2005-02-01
影响因子:
3.3
通讯作者:
Reichek, N
Reichek, N
中科院分区:
医学3区
文献类型:
--
作者:
Goldfarb, JW;Mathew, ST;Reichek, N

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本工作旨在开发和评价能够通过T、左心室血池和心肌节段中的测量值监测钆(Gd)浓度的屏气IR-TrueFISP采集的准确性。使用体模进行测量,以评估该技术的准确性。使用几种理论配方获得了造影剂给药后预期范围内的准确T,测量值。只有当成像段之间的延迟时间(TD)期间磁化的不完全恢复被纳入观察到的信号强度计算时,才能获得造影剂给药前的准确T值。在4名已知心肌梗死的受试者中进行了1小时时间段内的T,测量。在这项小型研究中,观察到了近期和陈旧性心肌梗死之间的Gd差异。(C)2005 Wiley-Liss,Inc.
The purpose of this work was to develop and evaluate the accuracy of a breath-hold IR-TrueFISP acquisition capable of monitoring gadolinium (Gd) concentrations through T, measurements in the left ventricular blood pool and segments of the myocardium over an extended duration. Measurements using a phantom were performed to assess the accuracy of the technique. Accurate T, measurements in the expected range after contrast agent administration were obtained with several theoretical formulations. Accurate T, values before the administration of the contrast agent were obtained only when the incomplete recovery of magnetization during the delay time (TD) between imaging segments was incorporated into the observed signal intensity calculations. T, measurements over a 1-hr time period were performed in four subjects with known myocardial infarctions. In this small study, Gd differences between recent and old myocardial infarctions were observed. (C) 2005 Wiley-Liss, Inc.