THE EFFECT OF 3 LEVELS OF INTAKE OF OSTERTAGIA-CIRCUMCINCTA LARVAE ON GROWTH-RATE, FOOD-INTAKE AND BODY-COMPOSITION OF GROWING LAMBS
THE EFFECT OF 3 LEVELS OF INTAKE OF OSTERTAGIA-CIRCUMCINCTA LARVAE ON GROWTH-RATE, FOOD-INTAKE AND BODY-COMPOSITION OF GROWING LAMBS
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DOI：
10.1017/s0021859600041782
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发表时间：
1982-01-01
影响因子：
2
通讯作者：
ANGUS, KW
中科院分区：
文献类型：
--
作者：
COOP, RL;SYKES, AR;ANGUS, KW
四莫将从出生起就无虫饲养的老年羔羊（48只）分配到6组，并随意提供含有139 g粗蛋白/kg DM [干物质]的完全饮食。一组在开始时被杀死作为初始对照（CI）。进一步的组，ALC，1，2，3和4每天给药0，1000，3000，5000和5000的O. circumcincta，分别。第4组羔羊在第21、42、63和84天也接受驱虫剂（芬苯达唑，5 mg/kg）。98天后处死羔羊，分析其尸体和初始对照组的尸体的脂肪、蛋白质和矿物质含量。没有羔羊显示出明显的感染临床体征，第1、2、3和4组屠宰时的平均奥斯特线虫负荷分别为6180、2880、5700和0。与ALC组相比，DM摄入量分别减少了5.6%、7.5%、12.2%和12.5%，活重增加仅为90%、75%、53%和66%。N的表观消化率降低了38-53%，在感染组的第4周，但恢复到控制水平，在第1和第4组的第7周，在第2组的第10周和第3组的第13周。第2、3和4组的体脂和蛋白质显著低于ALC组，第2和3组的胴体矿物质含量降低。第2、3和4组从第3周开始出现轻微低白蛋白血症。奥斯特线虫对血清总蛋白或尿素浓度无显著影响。皱胃的组织学检查显示，第1、2和3组中粘膜肥大伴壁细胞耗竭，第4组中仅出现轻度局灶性病变。> 1000只奥斯特线虫幼虫/天的摄入量降低了用于生长的代谢能的总利用率，并且这种影响不能通过定期使用驱虫剂消除。
Four-mo.-old lambs (48), reared worm-free from birth, were allocated to 6 groups and offered ad lib a complete diet containing 139 g crude protein/kg DM [dry matter]. One group was killed at the outset as initial control (CI). Further groups, ALC, 1, 2, 3 and 4 were dosed daily for 84 days with 0, 1000, 3000, 5000 and 5000 larvae of O. circumcincta, respectively. Lambs in group 4 also received anthelmintic (fenbendazole, 5 mg/kg) on days 21, 42, 63 and 84. Lambs were killed after 98 days and their carcasses and those of the initial controls analyzed for fat, protein and mineral contents. None of the lambs showed obvious clinical signs of infection and mean Ostertagia burdens at slaughter were 6180, 2880, 5700 and 0 for groups 1, 2, 3 and 4, respectively. DM intake was reduced by 5.6, 7.5, 12.2 and 12.5% and live-weight gain was only 90, 75, 53 and 66%, respectively, in groups 1-4 compared with values in group ALC. Apparent digestibility of N was reduced by 38-53% in the infected groups by wk 4, but returned to control levels in groups 1 and 4 by wk 7, in group 2 by wk 10 and group 3 by wk 13. Groups 2, 3 and 4 had significantly less body fat and protein than group ALC and the mineral content of the carcass was reduced in groups 2 and 3. Slight hypoalbuminemia developed from wk 3 in groups 2, 3 and 4. There was no significant effect of Ostertagia on serum total protein or urea concentrations. Histological examination of the abomasa showed mucosal hypertrophy with depletion of parietal cells in groups 1, 2 and 3 and only mild focal lesions in group 4. Intakes > 1000 Ostertagia larvae/day reduced the gross efficiency of use of metabolizable energy for growth and this effect was not eliminated by regular treatment with anthelmintic.