Tumor detection by virtual cystoscopy with color mapping of bladder wall thickness
Tumor detection by virtual cystoscopy with color mapping of bladder wall thickness
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DOI：
10.1016/s0022-5347(01)69085-2
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发表时间：
2002-02-01
影响因子：
6.6
通讯作者：
Kikinis, R
中科院分区：
文献类型：
--
作者：
Fielding, JR;Hoyte, L;Kikinis, R
目的：我们确定的价值，彩色映射膀胱壁厚度检测肿瘤作为一个组成部分，虚拟cystoscopy.Materials和方法：共31例血尿和/或膀胱肿瘤的历史进行了螺旋CT的骨盆扩张后的膀胱与空气。构建三维（D）模型，并根据固定且经验证的mm尺度对壁厚度进行颜色映射。对轴向源图像和3-D模型进行审查，并对壁增厚的存在进行分级。结果：与常规膀胱镜检查结果比较，轴位图像诊断膀胱肿瘤的敏感性为0.80，特异性为0.90，阳性预测值为0.80，阴性预测值为0.90。检查彩色映射的3-D渲染结果分别为0.83，0.36，0.42和0.71.Conclusions：薄轴向CT的空气膨胀膀胱显示作为一个潜在的筛查工具膀胱癌的承诺。彩色映射三维渲染的低特异性使得该技术不适合用于筛选。它可能有价值的指导泌尿科医生在一个已知的肿瘤患者的其他可疑部位。
Purpose: We determine the value of color mapping of bladder wall thickness for detection of tumor as a component of virtual cystoscopy.Materials and Methods: A total of 31 subjects with hematuria and/or a history of bladder tumor underwent helical computerized tomography of the pelvis after distention of the bladder with air. Three-dimensional (D) models were constructed, and thickness of the wall was color mapped according to a fixed and validated mm. scale. Axial source images and 3-D models were reviewed and graded for the presence of wall thickening. A comparison was made with findings on conventional cystoscopy in 31 patients and pathological specimen in 13.Results: Compared with conventional cystoscopy, the analysis of axial image yielded a sensitivity of 0.80, specificity 0.90, positive predictive value 0.80 and negative predictive value 0.90 for the presence of tumor. Examination of color mapped 3-D renderings resulted in 0.83, 0.36, 0.42 and 0.71, respectively.Conclusions: Thin axial computerized tomography of the air distended bladder shows promise as a potential screening tool for bladder cancer. The low specificity of color mapped 3-D renderings makes the technique inappropriate for screening. It may valuable for guiding urologists to additional suspicious sites in a patient with a known tumor.