The life-course impact of smoking on hypertension, myocardial infarction and respiratory diseases.
The life-course impact of smoking on hypertension, myocardial infarction and respiratory diseases.
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DOI：
10.1038/s41598-017-04552-5
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发表时间：
2017-06-28
影响因子：
4.6
通讯作者：
Wang W
中科院分区：
文献类型：
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作者：
Gao K;Shi X;Wang W
本研究的目的是探讨吸烟对呼吸系统疾病、高血压和心肌梗死的影响，特别是从生命过程的角度。在这项研究中，28,577名男性从中国的纵向调查进行了分析。分别从生命过程和当前观点评估吸烟对呼吸系统疾病、高血压和心肌梗死风险的影响。在35岁以下的人群中，吸烟与呼吸道疾病、高血压和心肌梗死的风险之间没有显著的联系。在36-55岁和56-80岁的研究参与者中，从生命过程的角度来看，吸烟与呼吸系统疾病、高血压和心肌梗死的风险呈正相关，并且风险随着年龄的增长而增加。相比之下，从目前的观点来看，吸烟与上述疾病的风险之间存在负相关。我们的研究结果强调，在未来的研究中，从生命过程的角度量化吸烟的影响是至关重要的，并建议吸烟者尽快戒烟，无论戒烟的暂时副作用如何。
The objective of this study was to examine the impact of smoking on respiratory diseases, hypertension and myocardial infarction, with a particular focus from a life-course perspective. In this study, 28,577 males from a Chinese longitudinal survey were analysed. The effects of smoking on the risk of respiratory diseases, hypertension and myocardial infarction were assessed from a life-course perspective and a current view separately. No significant associations were found between smoking and the risk of incident respiratory diseases, hypertension and myocardial infarction in the group younger than 35. Among study participants aged between 36–55 and 56–80, smoking was positively associated with the risk of incident respiratory diseases, hypertension and myocardial infarction from the life-course perspective, and the risk increased with age. In contrast, the results from a current view showed inverse associations between smoking and the risk of the diseases mentioned above. Our findings highlight that it is essential to quantify the effects of smoking from a life-course perspective in future research and to suggest that smokers quit smoking as soon as possible, regardless of the temporary side effects of quitting.