OPTICAL-PROPERTIES OF NORMAL AND CARCINOMATOUS BRONCHIAL TISSUE
OPTICAL-PROPERTIES OF NORMAL AND CARCINOMATOUS BRONCHIAL TISSUE
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DOI：
10.1364/ao.33.007397
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发表时间：
1994-11-01
期刊：
影响因子：
1.9
通讯作者：
PALCIC, B
中科院分区：
文献类型：
--
作者：
QU, JN;MACAULAY, C;PALCIC, B
为了更好地了解正常和癌支气管组织的光学特性和自身荧光特性，我们在400 ~ 700 nm范围内测量了吸收系数、散射系数和各向异性因子。我们使用带准直白光光束的积分球测量样品的全反射和透射率。通过轴向偏振光检测测量样品的非散射透过率。利用逆加倍解求解了辐射传递方程，确定了吸收系数和约化散射系数。散射系数和各向异性系数由样品的非散射透过率和简化后的散射系数得到。测量参数允许我们模拟光子在正常支气管和肿瘤组织中的传播使用蒙特卡罗模型。
understand better the optical characteristics and autofluorescence properties of normal and carcinomatous bronchial tissue, we measured the absorption coefficient, scattering coefficient, and anisotropy factor from 400 to 700 nm. We made the measurements by using an integrating sphere with a collimated white-light beam to measure total reflectance and transmittance of samples. The unscattered transmittance of the samples was measured through polarized on-axis light detection. The inverse adding-doubling solution was utilized to solve the equation of radiative transfer and to determine the absorption coefficient and reduced scattering coefficient. The scattering coefficient and anisotropy factor were derived from the unscattered transmittance of the sample and the reduced scattering coefficient. The measured parameters allow us to simulate photon propagation in normal bronchial and tumoral tissue by using Monte Carlo modeling.