Efficient Sampling Windows for Parameter Estimation in Mixed Effects Models

Efficient Sampling Windows for Parameter Estimation in Mixed Effects Models
复制标题

混合效应模型中参数估计的高效采样窗口

DOI:
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发表时间:
2007
期刊:
影响因子:
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通讯作者:
B. Bogacka
B. Bogacka
中科院分区:
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文献类型:
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作者:
M. Patan;B. Bogacka

文献摘要

被引文献

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本文提出了一种计算非线性混合效应模型参数估计的有效窗设计的方法。我们定义了一个窗口人口设计的基础上,这样一个模型的连续设计。设计的支撑点属于区间,其边界以确保设计效率高的方式确定;区间的宽度也与动态系统的行为有关。
In the paper we present a method of calculating an efficient window design for parameter estimation in a non-linear mixed effects model. We define a window population design on the basis of a continuous design for such a model. The support points of the design belong to intervals whose boundaries are determined in a way which ensures that the efficiency of the design is high; also the width of the intervals is related to the dynamic system’s behaviour.