Idiopathic Infantile Pyoderma Gangrenosum with Stridor Responsive to Infliximab

Idiopathic Infantile Pyoderma Gangrenosum with Stridor Responsive to Infliximab
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对英夫利昔单抗有反应的特发性婴儿坏疽性脓皮病伴喘鸣

DOI:
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发表时间:
2009
影响因子:
1.5
通讯作者:
A. Carmichael
A. Carmichael
中科院分区:
医学4区
文献类型:
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作者:
N. Rajan;Sharmila Das;A. Taylor;M. Abinun;D. Spencer;A. Carmichael

文献摘要

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翻译后摘要:一个4个月大的女婴广泛脓坏疽与喘鸣,推测继发于气管受累。 尽管进行了广泛的调查,但没有发现根本原因。免疫抑制剂治疗仅部分抑制疾病活动。英夫利西单抗治疗后完全消退。我们回顾了这种罕见的情况下,婴儿和讨论治疗英夫利昔单抗以前没有描述在这个年龄组。
Abstract:  A 4‐month‐old female infant presented with widespread pyoderma gangrenosum associated with stridor, presumed secondary to tracheal involvement. No underlying cause was revealed despite extensive investigation. Treatment with immunosuppressive agents only partially suppressed disease activity. Complete resolution followed treatment with infliximab. We review this rare condition in infants and discuss treatment with infliximab not previously described in this age group.