The investigation of placental relaxation and estimation of placental perfusion using echo-planar magnetic resonance imaging
The investigation of placental relaxation and estimation of placental perfusion using echo-planar magnetic resonance imaging
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DOI：
10.1016/s0143-4004(98)91048-7
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发表时间：
1998-09-01
期刊：
影响因子：
3.8
通讯作者：
Johnson, IR
中科院分区：
文献类型：
--
作者：
Duncan, KR;Gowland, P;Johnson, IR
回波平面成像（EPI）是磁共振成像（MRI）的一种形式，它在毫秒而不是传统MRI的几分钟内获取图像。使用EPI产生的图像受到生理环境的影响，其中发现了产生信号的氢原子，这一过程被称为弛豫。而且，通过产生大约几毫秒间隔的图像，被成像的组织内的灌注的量化是可行的。本研究的目的是调查T1和T2弛豫时间沿着灌注在胎盘从正常妊娠在不同的妊娠，也比较这些妊娠并发异常胎盘功能。对20周至足月的正常和受损妊娠进行横断面研究，并对正常妊娠进行纵向研究。胎盘T1，T2弛豫时间和灌注测量使用回波平面磁共振成像。正常妊娠组胎盘T1、T2弛豫时间缩短（P
Echo-planar imaging (EPI) is a form of magnetic resonance imaging (MRI) which acquires images in milliseconds rather than minutes as with conventional MRI. The images produced using EPI are affected by the physiological environment in which the hydrogen atoms producing the signals are found, a process referred to as relaxation. Also by producing images a matter of milliseconds apart, quantification of perfusion within the tissue being imaged is feasible. The objective of this study was to investigate T1 and T2 relaxation times along with perfusion in placentae from normal pregnancies at different gestations and also to compare these to pregnancies complicated by abnormal placental function. A cross-sectional study of normal and compromised pregnancies from 20 weeks to term and a longitudinal study of normal pregnancy were performed. Placental T1, T2 relaxation times, and perfusion were measured using echo-planar magnetic resonance imaging. Placental T1 and T2 relaxation times decreased in normal pregnancy (P