Iron Thiolate Complexes: Efficient Catalysts for Coupling Alkenyl Halides with Alkyl Grignard Reagents
Iron Thiolate Complexes: Efficient Catalysts for Coupling Alkenyl Halides with Alkyl Grignard Reagents
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DOI：
10.1002/chem.201200184
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发表时间：
2012-05-01
影响因子：
4.3
通讯作者：
Patinote, Cindy
中科院分区：
文献类型：
--
作者：
Cahiez, Gerard;Gager, Olivier;Patinote, Cindy
熨平扭结：介绍了一种基于硫醇铁的新型高效催化体系，用于铁催化烷基格氏试剂与卤代烯基的交叉偶联反应。该反应具有高度的化学和立体选择性。采用这种新方法，不再需要使用N-甲基吡咯烷酮作为共溶剂。
Ironing out the kinks: Efficient new catalytic systems based on iron thiolates are described for the iron-catalyzed cross-coupling of alkyl Grignard reagents with alkenyl halides. The reaction is highly chemo-and stereoselective. With this new procedure, the use of N-methylpyrrolidone as a co-solvent is no longer required.