Advancing a real-time image-based jet lag tracking methodology for optimizing print parameters and assessing melt electrowritten fiber quality
Advancing a real-time image-based jet lag tracking methodology for optimizing print parameters and assessing melt electrowritten fiber quality
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DOI：
10.1016/j.addma.2022.102764
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发表时间：
2022-03
影响因子：
11
通讯作者：
K. Cao;Fucheng Zhang;A. Zaeri;Ralf Zgeib;R. Chang
中科院分区：
文献类型：
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作者：
K. Cao;Fucheng Zhang;A. Zaeri;Ralf Zgeib;R. Chang
熔融电写(MEW)已成为制备高分辨率微米级纤维支架的重要添加剂，用于组织工程应用。然而，众多工艺变量之间的复杂相互作用使得这种添加剂制造技术的参数优化成为一项具有挑战性的任务。为了便于Mew-Jet纤维制造的优化，本研究采用了一种实时时差跟踪方法。具体地说，这种方法的实施是为了确定改善纤维质量的最佳条件，其特征是规定的平均直径和增强的整齐度。首先，设计了一条蛇形刀具轨迹，并实时记录了时差信号，呈现出多个连续的峰值。与这些峰值相关的变异系数CVpv首次被确定为时差稳定性的指标。其次，对于给定的压力(P)和平移阶段速度(V)，随着施加电压(U)的增加，CVpvis在达到最小点ATU=UC之前开始减小，然后在较高的U值时增加。否则，当U&gT；UC时，以可检测到的漏电为代价来实现增强的光纤均匀性。此外，在给定的P处，asv减小，Uc减小，而在ValueUb处停滞。此外，UBIS发现随着P值的增加而增加。这些依赖关系与泰勒锥周围的质量平衡密切相关。最后，基于这些结果，提出了一种系统的方案，以确定能够增强印花纤维质量的适当的P-U-V设置。
Melt electrowriting (MEW) has emerged as an important additive manufacturing process to fabricate high-resolution microscale fibrous scaffolds for engineered tissue applications. However, the complex interplay between the numerous process variables renders parametric optimization of this additive manufacturing technique a challenging task. In order to facilitate the optimization of MEW-jetted fiber fabrication, this study adopts a real-time jet lag tracking methodology. Specifically, this methodology is implemented to determine the optimum conditions to improve the fiber quality featured by a prescribed mean diameter and an enhanced uniformity. Firstly, a serpentine toolpath is designed, and the real-time jet lag length signal is recorded, exhibiting multiple successive peaks. The coefficient of varianceCVpvcorrelated with these peak values is first identified as an indicator of the jet lag stability. Second, for a given pressure (P) and translational stage speed (v), as the applied voltage (U) increases,CVpvis found to initially decrease before reaching a minimum point atU=Uc, followed by an increase at higherUvalues.Ucrepresents an inflection point on the graph ofCVpvas a function ofU, whereby fiber pulsing is observed whenU<Uc. Otherwise, an enhanced fiber uniformity is achieved at the expense of detectable current leakage whenU>Uc. Moreover, at a givenP, asvdecreases,Ucdeceases and plateaus at a valueUb. Furthermore,Ubis found to increase asPincreases. These aforementioned dependencies are closely related to the mass equilibrium around the Taylor cone. Finally, based on these results, a systematic protocol is advanced to determine the appropriateP-U-vsettings that enable an enhanced printed fiber quality.