Risk Factors and Impacts of Incident Tinnitus in Older Adults
Risk Factors and Impacts of Incident Tinnitus in Older Adults
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DOI：
10.1016/j.annepidem.2009.09.002
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发表时间：
2010-02-01
影响因子：
5.6
通讯作者：
Mitchell, Paul
中科院分区：
文献类型：
--
作者：
Gopinath, Bamini;McMahon, Catherine M.;Mitchell, Paul
目得：我们使用了一个有代表性的老年人口为基础的队列，以建立耳鸣的预测因素和影响。方法：共1,214名参与者的蓝山听力研究进行了为期5年（1997-1999年至2002-2004年）。耳鸣的存在进行了评估，由听力学家管理的问卷调查。听力障碍定义为听力较好耳的纯音平均（PTA）（0.5-4KHz）> 25 dB HL。生活质量通过使用简明健康调查表（SF-36）进行测量。使用SF-36评估抑郁症（心理健康指数，分量表）和流行病学研究中心抑郁量表。症状性头晕和听力损失是耳鸣发生的重要危险因素，多变量校正比值比为2.41（95%可信区间，1.62-3.58）和比值比2.31（95%可信区间，1.46-3.66）。事件耳鸣的情况下，表现出显着较低的平均SF-36评分与受试者相比，没有耳鸣，更容易被抑郁的心理健康指数和流行病学研究中心抑郁Scale.CONCLUSIONS：事件耳鸣预测两个耳科危险因素，头晕和听力损失。时间数据记录了耳鸣患者的生活质量和心理健康状况下降。这一发现强调了有效的干预策略的重要性，以防止潜在的衰弱与耳鸣相关的发病率。Ann Epidemiol 2010;20：129-135. (C)2010年爱思唯尔公司All rights reserved.
PURPOSE: We used a representative older population-based cohort to establish the predictors and impacts of tinnitus.METHODS: A total of 1,214 participants of the Blue Mountains Hearing Study were followed for 5 year; (1997-1999 to 2002-2004). The presence of tinnitus was assessed by an audiologist-administered questionnaire. Hearing impairment was defined as the pure tone average (PTA)(0.5-4KHz) > 25 dB HL, in the better ear. Quality of life was measured by use of the Short Form 36-item Health Survey (SF-36). Depression was assessed using either the SF-36 (Mental Health Index, subscale) and the Center for Epidemiologic Studies Depression Scale.RESULTS: Symptomatic dizziness and hearing loss were significant risk factors for incident tinnitus, multivariable-adjusted odds ratio, 2.41 (95% confidence interval, 1.62-3.58) and odds ratio 2.31 (95% confidence interval, 1.46-3.66), respectively. Incident tinnitus cases demonstrated significantly lower mean SF-36 scores compared with subjects without tinnitus and were more likely to be depressed as assessed by both the Mental Health Index and Center for Epidemiologic Studies Depression Scale.CONCLUSIONS: Incident tinnitus was predicted by two otological risk factors, dizziness and hearing loss. Temporal data documented diminished quality of life and psychological well-being in those subjects experiencing tinnitus. This finding highlights the importance of effective intervention strategies to prevent potentially debilitating morbidity associated with tinnitus. Ann Epidemiol 2010;20:129-135. (C) 2010 Elsevier Inc. All rights reserved.