Spinal cysticercosis: a rare cause of myelopathy.
Spinal cysticercosis: a rare cause of myelopathy.
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脊髓囊尾蚴病：脊髓病的罕见原因
DOI：
10.1186/s12883-022-02589-2
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发表时间：
2022-02-22
期刊：
影响因子：
2.6
通讯作者：
Xu Y
中科院分区：
文献类型：
--
作者：
Yang C;Liu T;Wu J;Xie J;Yu T;Jia W;Yang J;Xu Y
神经囊尾蚴病是一种由猪带绦虫幼虫期引起的神经传染病。孤立性脊髓囊尾蚴病很少见，文献中报道的病例有限。该实体带来了巨大的诊断和治疗挑战。这项回顾性研究包括七名经病理诊断患有脊髓囊尾蚴病的患者。分析了临床表现、磁共振成像（MRI）放射学特征、治疗和结果。该病例系列包括 4 名男性和 3 名女性患者，平均年龄为 34.9±10.9 岁。临床上，六名患者表现为定位相关性脊髓病。有 4 个实性病变、1 个囊性实性病变和 3 个囊性病变。实性和囊性实性病灶具有特征性MRI特征：1）病灶内存在附壁结节，T1WI为等信号，T2WI为等至高信号； 2）T2WI上附壁结节周边信号变化，从低信号到高信号； 3)可出现环状或囊壁强化，壁结节内可见点状强化。所有患者均实现了相关病灶的完全切除，并对一名疑似有同源病灶的患者给予口服阿苯达唑。经过平均56.7±35.1个月的随访，患者的症状大部分消退。脊髓囊尾蚴病是脊髓病的一种极其罕见的原因。特征性 MRI 特征有助于术前诊断。临床医生应该了解这一实体，并将其纳入脊髓病的鉴别诊断中。
Neurocysticercosis is a neuroinfectious disease caused by the larval stage of the tapeworm Taenia solium. Isolated spinal cysticercosis is rare, with limited cases having been reported in the literature. This entity poses great diagnostic and therapeutic challenges. This retrospective study included seven patients pathologically diagnosed with spinal cysticercosis. The clinical manifestations, radiological features on magnetic resonance imaging (MRI), treatment, and outcomes were analyzed. This case series consisted of four male and three female patients, with an average age of 34.9 ± 10.9 years. Clinically, six patients manifested with localization-related myelopathy. There were four solid lesions, one cystic-solid lesion, and three cystic lesions. The solid and cystic-solid lesions showed characteristic MRI features: 1) within the lesion, there was a mural nodule with isointensity on T1WI and iso- to hyperintensity on T2WI; 2) the signals at the periphery of the mural nodule were variable, ranging from hypointense to hyperintense on T2WI; and 3) ring-like or cyst wall enhancement could be present, and dot-like enhancement could be noted in the mural nodule. Complete resection of the responsible lesion was achieved in all patients, and oral albendazole was administered in a patient with one more suspected homologous lesion. After a mean follow-up period of 56.7 ± 35.1 months, the patient’s symptoms mostly regressed. Spinal cysticercosis is an extremely rare cause of myelopathy. Characteristic MRI features can facilitate preoperative diagnosis. Clinicians should be aware of this entity, and it should be included in the differential diagnosis of myelopathy.
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DOI：
10.1016/b978-0-7020-4088-7.00097-3
发表时间：
2014-10-01
期刊：
The Neurohospitalist
影响因子：
--
作者：
Del Brutto, Oscar H
通讯作者：
Del Brutto, Oscar H
影响因子：
9.9
作者：
Callacondo, D.;Garcia, H. H.;Nash, T. E.
通讯作者：
Nash, T. E.
影响因子：
0.5
作者：
Azfar, Shah F.;Kirmani, Sanna;Ahmad, Ibne
通讯作者：
Ahmad, Ibne
影响因子：
4.4
作者：
Del Brutto, Oscar H.;Garcia, Hector H.
通讯作者：
Garcia, Hector H.
影响因子：
0.9
作者：
Lin, Jiangkai;Chu, Weihua;Ye, Xinzhen
通讯作者：
Ye, Xinzhen