[Gastrin ].
[Gastrin ].
复制标题
[胃泌素]。
DOI：
10.1007/springerreference_173988
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发表时间：
1968
期刊：
影响因子：
0.6
通讯作者：
V. Vince
中科院分区：
文献类型：
--
作者：
V. Vince
Zantac ®、Prilosec ®和pepsid干扰胃泌素的产生。临床背景胃泌素是由胃窦粘膜G细胞和十二指肠近端细胞分泌的一种多肽激素。胃泌素是胃窦酸分泌的有效刺激物，并且还对泌酸粘膜中的壁细胞、主细胞和肠嗜铬样细胞具有营养作用。胃泌素水平随着食物摄入量（蛋白质，氨基酸）和年龄的增加而增加。水平随着胃酸分泌而降低。
Zantac®’, Prilosec®’, and pepsid interfere with gastrin production. Clinical Background Gastrin is a polypeptide hormone secreted by the G cells of the gastric antral mucosa and proximal duodenal cells. Gastrin is a potent stimulator of antral acid secretion, and also has trophic actions on the parietal cells, chief cells, and enterochromaffin-like cells in the oxyntic mucosa. Gastrin levels increase with food intake (protein, amino acids) and age. Levels decrease with gastric acid secretion.