Asymmetric autocatalysis triggered by oxygen isotopically chiral glycerin
Asymmetric autocatalysis triggered by oxygen isotopically chiral glycerin
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DOI：
10.1039/c3ob40293b
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发表时间：
2013-01-01
影响因子：
3.2
通讯作者：
Soai, Kenso
中科院分区：
文献类型：
--
作者：
Matsumoto, Arimasa;Oji, Shotaro;Soai, Kenso
手性(S)-和(R)- o -18-甘油诱导了二异丙基锌对嘧啶-5-乙醛的选择性加成，随后的不对称自催化作用分别产生了(R)-和(S)-嘧啶烷基醇对映体过量。
Chiral (S)- and (R)-O-18-glycerin induces enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, and the subsequent asymmetric autocatalysis affords (R)- and (S)-pyrimidyl alkanol with high enantiomeric excess, respectively.