Evaluation of dairy allergy among ulcerative colitis patients.
Evaluation of dairy allergy among ulcerative colitis patients.
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DOI：
10.6026/97320630010693
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发表时间：
2014
期刊：
影响因子：
1.9
通讯作者：
Alizadeh S
中科院分区：
文献类型：
--
作者：
Judaki A;Hafeziahmadi M;Yousefi A;Havasian MR;Panahi J;Sayehmiri K;Alizadeh S
肠道是人体最大的粘膜器官，也是维持免疫稳态的第一线。炎症性肠病或IBD分为溃疡性结肠炎和克罗恩病。UC可能发生的问题之一是对某些食物的饮食过敏。本研究旨在评估溃疡性结肠炎患者对乳制品过敏的情况。本研究为病例对照研究，对72例溃疡性结肠炎患者（记录病史、结肠镜检查并经活检证实）和72例无结肠炎病史者进行研究。在本研究中，为了调查食物过敏，使用了国际代码为DP 3420 -1601- 11 E的EUROMMUM试剂盒。我们使用卡方和蒙特卡罗方法对数据进行分析。UC患者中轻度占30.6%，中度占52.8%，重度占16.6%。9.7%的患者报告有因疾病进行腹部手术的病史。根据卡方检验和蒙特卡罗方法，UC组的乳制品过敏（包括：牛奶、牛奶UHT和酪蛋白）有显著性差异（P=0.00）。本研究表明，UC与牛乳、牛乳超高温灭菌和酪蛋白有显著的相关性。对乳制品过敏的UC患者和乳制品的使用可增加UC的严重程度。
The intestine is the largest mucosal organ of the body and also the first line immune homeostasis. Inflammatory bowel disease or IBD is divided into ulcerative colitis and Crohn's disease. One of the problems that can occur with UC is dietary allergy to some foods. This study aimed to evaluated the dairy allergy among patients with ulcerative colitis. This study is a Case - control study, that studied 72 patients with Ulcerative Colitis, after recording history of the disease, colonoscopy and confirmed by biopsy and 72 person without history of colitis. In this study, in order to investigate of food allergy, used of the EUROMMUM kit with an international code number DP3420-1601-11E. We used chi-square and Monte Carlo method for analysis of data. Among UC patients, 30.6% mild, 52.8% moderate and 16.6% of cases were in sever stage. 9.7% of them reported a history of abdominal surgery due to disease. According to the chi-square and Monte Carlo methods, dairy allergy (including: cow milk, cow milk UHT and casein) in UC group was significant (P=0.00). This study indicated that there is significant relationship between UC and cow milk, cow milk UHT and casein. UC patients who are allergic to dairy products and the use of dairy products can increase the severity of UC.