A MEMS-based flexible multichannel ECoG-electrode array
A MEMS-based flexible multichannel ECoG-electrode array
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DOI：
10.1088/1741-2560/6/3/036003
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发表时间：
2009-06-01
影响因子：
4
通讯作者：
Stieglitz, Thomas
中科院分区：
文献类型：
--
作者：
Rubehn, Birthe;Bosman, Conrado;Stieglitz, Thomas
我们提出了一种微机械252通道皮层脑电图（ECoG）电极阵列，它是由薄聚酰亚胺箔基板包围溅射铂电极网站和导体路径。该阵列对着约35 mm × 60 mm的区域，并被设计为覆盖猕猴皮质半球的大部分。八个omnetics连接器直接焊接到箔。这导致紧凑的组件尺寸，其使得能够长期植入阵列并且允许动物在记录会话之间自由移动。电极位点直径为1 mm，并通过电化学阻抗谱进行表征。在1 kHz。电极阻抗在1.5k Ω和5k Ω之间变化。在三个组装的装置中，功能电极的产率为99.5%。在植入具有100%工作电极的装置后，可以从每个电极获得标准的皮层电图信号。对视觉刺激的反应可以用位于视觉皮层上的电极来测量。植入4.5个月后，所有电极仍在工作，未观察到信号质量下降。
We present a micromachined 252-channel ECoG (electrocorticogram) -electrode array, which is made of a thin polyimide foil substrate enclosing Sputtered platinum electrode sites and conductor paths. The array subtends an area of approximately 35 mm by 60 mm and is designed to cover large parts of a hemisphere of a macaque monkey's cortex. Eight omnetics connectors are directly soldered to the foil. This leads to a compact assembly size which enables a chronic implantation of the array and allows free movements of the animal between the recording sessions. The electrode sites are 1 mm in diameter and were characterized by electrochemical impedance spectroscopy. At 1 kHz. the electrode impedances vary between 1.5 k Omega and 5 k Omega. The yield of functioning electrodes in three assembled devices is 99.5%. After implantation of a device with 100% working electrodes, standard electrocorticographic signals can be obtained from every electrode. The response to Visual stimuli can be measured with electrodes lying on the Visual cortex. After an implantation time of 4.5 months, all electrodes are still working and no decline in signal quality Could be observed.