Preoperative evaluation of oral tongue squamous cell carcinoma with intraoral ultrasound and magnetic resonance imaging-comparison with histopathological tumour thickness and accuracy in guiding patient management
Preoperative evaluation of oral tongue squamous cell carcinoma with intraoral ultrasound and magnetic resonance imaging-comparison with histopathological tumour thickness and accuracy in guiding patient management
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DOI：
10.1016/j.ijom.2013.12.009
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发表时间：
2014-07-01
影响因子：
2.4
通讯作者：
Phal, P. M.
中科院分区：
文献类型：
--
作者：
Yesuratnam, A.;Wiesenfeld, D.;Phal, P. M.
本研究的目的是调查肿瘤厚度（TT）的口腔内超声（US）和磁共振成像（MRI）与组织学确定的舌癌TT之间的相关性。次要目的包括评价影响这种关联的潜在混杂因素和同时进行颈清扫术的预测价值。对2007年1月至2012年8月期间转诊至研究机构的88例推定诊断为舌浸润性鳞状细胞癌（SCC）的连续患者进行了分析。79例患者术前进行了US检查，81例患者进行了MRI检查。通过Bland-Altman图和Pearson相关系数评估图像确定的TT和组织学TT之间的相关性。通过亚组分析评估潜在混杂因素。术前超声TT与组织学TT高度相关，MRI与组织学TT中度相关。亚组分析显示，与浸润性鳞状细胞癌相比，影像学检查前活检和切除术诊断与浸润性鳞状细胞癌呈负相关。我们的经验表明，US可以被认为是术前评估TT的首选方式。
The aim of this study was to investigate the correlation between tumour thickness (TT) on intraoral ultrasound (US) and magnetic resonance imaging (MRI) with the histologically determined TT of tongue cancers. Secondary objectives included evaluation of potential confounders that affect this association and the predictive value for simultaneous neck dissection. Eighty-eight consecutive patients referred to the study institution between January 2007 and August 2012 with the presumptive diagnosis of invasive squamous cell carcinoma (SCC) of the tongue were analyzed. Seventy-nine patients had preoperative US and 81 had MRI. Correlation between image-determined TT and histological TT was assessed by Bland-Altman plot and Pearson's correlation coefficient. Potential confounders were assessed by subgroup analysis. Preoperative TT as determined by US demonstrated high correlation and MRI moderate correlation with histological TT. With subgroup analysis, negative associations were biopsy prior to imaging and resection diagnosis other than invasive SCC. Our experience suggests that US could be considered the initial modality of choice for preoperative assessment of TT.