FUNDUS AUTOFLUORESCENCE AND MULTIPLE EVANESCENT WHITE DOT SYNDROME
FUNDUS AUTOFLUORESCENCE AND MULTIPLE EVANESCENT WHITE DOT SYNDROME
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DOI：
10.1097/iae.0b013e31818c5e04
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发表时间：
2009-01-01
影响因子：
3.3
通讯作者：
Sborgia, Carlo
中科院分区：
文献类型：
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作者：
Furino, Claudio;Boscia, Francesco;Sborgia, Carlo
目的：观察多发性消失性白点综合征患者眼底自身荧光（FAF）的变化。方法：对3例多发性消失性白点综合征患者的3只眼进行吲哚青绿血管造影和FAF成像，评价FAF与ICG的对应关系以及ICG明显的局灶性低青点的性质。结果：急性期三眼自身荧光面积均增加，与ICG所见的局灶性低青光斑位置完全一致，但数量较少。2个月后，平均最佳矫正视力由20/38提高到20/20，FAF和吲胺绿血管造影恢复正常。讨论：FAF是一种有用的无创诊断辅助手段，用于识别多发性消失性白点综合征，提示疾病的炎症性质，可能是由于光感受器-视网膜色素上皮复合体的扰动影响了这些细胞的功能。
Objective: To describe fundus autofluorescence (FAF) in a series of patients with multiple evanescent white dot syndrome.Methods: Three eyes of three patients with multiple evanescent white dot syndrome were evaluated with indocyanine green angiography and FAF imaging to evaluate the correspondence between FAF and ICG patterns and the nature of the focal hypocyanescent spots evident with ICG.Results: In the acute phase, all three eyes showed increased autofluorescence area corresponding precisely to the site of the focal hypocyanescent spots seen on ICG but less numerous. After 2 months, mean best-corrected visual acuity improved from 20/38 to 20/20 and FAF and indocyanine green angiography returned to normal pattern.Discussion: FAF is an useful noninvasive diagnostic adjunct to identify multiple evanescent white dot syndrome, suggesting the inflammatory nature of the disease, probably due to perturbation of the photoreceptor-retinal pigment epithelium complex affecting the function of these cells.