Transport and utilization in insect flight muscles
Transport and utilization in insect flight muscles
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DOI：
10.1016/s0305-0491(97)00185-5
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发表时间：
1997-08-01
影响因子：
2.2
通讯作者：
Haunerland, NH
中科院分区：
文献类型：
--
作者：
Haunerland, NH
在鳞翅目和直翅目昆虫的迁徙中，脂类是持续飞行活动的首选燃料。二酰甘油由脂蛋白输送到飞行肌肉，并被水解成游离脂肪酸和甘油。脂肪酸以一种未知的机制穿透质膜后，被细胞内脂肪酸结合蛋白(FABP)结合，并通过细胞质运输。脂肪酸转化为酰基辅酶A酯后，通过肉碱穿梭进入线粒体基质，进行随后的P-氧化。本文综述了昆虫飞行肌脂代谢的研究现状，重点介绍了FABP的结构、功能及其在蝗虫发育和飞行过程中的表达。(C)1997年爱思唯尔科学公司。
In migrating lepidopteran and orthopteran insects, lipid is the preferred fuel for sustained flight activity. Diacylglycerol is delivered by lipophorin to the flight muscle and hydrolyzed to free fatty acid and glycerol. After penetrating the plasma membrane by an unknown mechanism, fatty acids are bound by the intracellular fatty acid binding protein (FABP) and transported through the cytosol. After their conversion to acyl-CoA esters, the fatty acids enter the mitochondrial matrix via the carnitine shuttle for subsequent P-oxidation. This article reviews the current knowledge of lipid metabolism in insect flight muscle, with particular emphasis on the structure and function of FABP and its expression during locust development and flight. (C) 1997 Elsevier Science Inc.