Diagnosis in Infants and Children With Osteogenesis Imperfecta.
Diagnosis in Infants and Children With Osteogenesis Imperfecta.
复制标题
婴儿和儿童成骨不全的诊断。
DOI：
10.1097/bpo.0000000000000564
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Donnaruma-Kwoh,Marcella
中科院分区：
文献类型：
--
作者：
Greeley,ChristopherS;Donnaruma-Kwoh,Marcella
回复：我们感谢谢尔默丁博士、阿尔瑟斯博士和考尔德博士对我们的文章《婴幼儿和儿童成骨不全时的骨折诊断》的兴趣。1我们想解决作者在信中提出的问题，2因为我们认为这些问题源于对我们研究目的和方法的误解。首先，谢尔默丁博士和他的同事批评我们的研究既没有对照组，也没有在所有主题上进行“基因测试和忏悔”。我们认为，这种批评是没有根据的，源于对我们研究目的的误解。正如我们的论文所述，这项研究的目的是纯粹的描述性。我们声明这项研究的目的是“确定临床医生在诊断患有OI的婴儿和儿童样本时所依赖的骨折类型和临床信息的特征。”1虽然我们假设存在模式差异，但我们谨慎地不声明我们的研究旨在证明这一点。由于诊断儿童成骨不全(OI)时的骨折类型以前没有描述过，我们认为，现在仍然如此，开始识别骨折类型是否确实存在真正的重叠是有价值的。虽然我们的数据仅限于回顾图表，但并没有显示出与虐待婴儿受害者经常描述的骨折模式有任何相似之处。我们认识到，我们的“患有多发性肋骨骨折的婴儿不太可能患有未诊断的OI”这一说法，对谢尔默丁博士和他的同事来说似乎是慷慨的。鉴于我们的研究是
In reply: We are grateful for Drs Shelmerdine, Arthurs, and Calder’s interest in our article “Fractures at diagnosis in infants and children with osteogenesis imperfecta.” 1 We would like to address the concerns raised by the authors in their letter, 2 as we believe that they arise from a misunderstanding of the intent and methodology of our study.First, Dr Shelmerdine and colleagues criticize our study as both not having a control group and not undertaking “genetic testing and confessionals” on all subjects. We believe that this criticism is unwarranted and stems from a misunderstanding of the purpose of our study. As stated in our paper, the study was intended to be purely descriptive in nature. We stated that the purpose of the study was to “characterize the fracture patterns and clinical information relied upon by clinicians at the time of diagnosis in a sample of infants and children with OI.” 1 While we hypothesized that the pattern difference would exist, we were careful not to state that our study was designed to demonstrate that. As fracture patterns at the time of diagnosis of osteogenesis imperfecta (OI) in children had not been described prior, we felt, and still do, that there is value to begin to identify if a true overlap of fracture pattern does indeed exist. Our data, while limited to a retrospective chart review, did not demonstrate any similarity to fracture patterns often described in infant victims of abuse. We recognize that our statement “infants with multiple rib fractures are unlikely to be suffering from undiagnosed OI” may seem generous to Dr Shelmerdine and colleagues. Given that our study is the
婴儿期成骨不全和肋骨骨折。
DOI：
10.1097/bpo.0000000000000149
发表时间：
2014
期刊：
Journal of pediatric orthopedics
影响因子：
--
作者：
C. Paterson
通讯作者：
C. Paterson
成骨不全症中的肋骨骨折：我们是否了解有关虐待儿童的任何信息？
DOI：
10.1097/bpo.0000000000000508
发表时间：
2015
期刊：
Journal of pediatric orthopedics
影响因子：
--
作者：
S. Shelmerdine;O. Arthurs;A. Calder
通讯作者：
A. Calder